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Compound synergistic tartaric acid tylosin for injection of livestock

A technology for injection of tylosin tartrate, which is applied in the direction of antibacterial drugs, pharmaceutical formulas, and medical preparations containing active ingredients, etc. It can solve the problems of incomplete curative effect and achieve long-lasting drug effect and definite curative effect , the effect of accurate dosage

Inactive Publication Date: 2012-11-21
SICHUAN DERUNTONG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The dosage of the injection is accurate and the effect is reliable, unlike the oral medicine that may be affected by digestive juices, food, etc., so that the dose taken cannot fully produce the curative effect

Method used

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  • Compound synergistic tartaric acid tylosin for injection of livestock
  • Compound synergistic tartaric acid tylosin for injection of livestock
  • Compound synergistic tartaric acid tylosin for injection of livestock

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, citric acid 0.2g, procaine hydrochloride 0.05g.

[0032] Preparation:

[0033] Respectively take trimethoprim and citric acid of the prescribed amount, mix them and pulverize them through a flow energy mill, pass through a 120 mesh sieve, and then deliver them in equal amounts with tylosin tartrate, kanamycin sulfate, and procaine hydrochloride. Addition, mixing evenly, inspection of semi-finished products, packaging, packaging, inspection of finished products, that is to say.

Embodiment 2

[0035] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, succinic acid 0.2g, procaine hydrochloride 0.05g.

[0036] Preparation:

[0037] Weigh respectively the prescribed amount of trimethoprim and succinic acid, mix them and pulverize them through a flow energy mill, pass through a 120-mesh sieve, and then add them with tylosin tartrate, kanamycin sulfate, and pain relieving agents in equal amounts. Mix evenly, inspect the semi-finished product, subpackage, pack, inspect the finished product, and put it into storage.

Embodiment 3

[0039] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, citric acid 0.2g, lidocaine hydrochloride 0.05g.

[0040] Preparation:

[0041] Respectively weigh trimethoprim and citric acid in the prescribed amount, mix them, pass through a flow energy mill, pass through a 150-mesh sieve, and then mix them with tylosin tartrate, kanamycin sulfate, and pain relieving agents in equal increments Uniformity, inspection of semi-finished products, sub-packaging, packaging, inspection of finished products, warehousing, and ready to go.

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Abstract

The invention relates to a compound synergistic tartaric acid tylosin for injection of livestock and aims at providing a compound synergistic tartaric acid tylosin, which can be used for achieving a rapid and definite curative effect on the breathing system infection and complications of livestock, for injection of livestock. The medicine comprises the following components in parts by weight: 1 part of tartaric acid tylosin, 1 part of kanamycin sulfate, 0.2 parts of trimethoprim, 0.2 parts of cosolvent and 0.05-0.1 parts of pain alleviator, wherein the cosolvent is citric acid or succinic acid or a combination of the citric acid and the succinic acid; and the pain alleviator is procaine hydrochloride or lidocaine hydrochloride or a combination of procaine hydrochloride and the lidocaine hydrochloride. The compound synergistic tartaric acid tylosin for injection of livestock contains medicine components of three types, namely tartaric acid tylosin, kanamycin sulfate and trimethoprim, can be used for solving the problems that tartaric acid tylosin is narrow in antimicrobial spectrum and cannot well control secondary infection during the treatment of mycoplasma infection and the problem that trimethoprim is insoluble in water, and achieving a synergy effect on tartaric acid tylosin and kanamycin sulfate, and is accurate in dosage and convenient in use.

Description

technical field [0001] The invention relates to compound synergistic tylosin tartrate for veterinary injection. Background technique [0002] Judging from the current development of my country's animal husbandry industry, the current high incidence of respiratory infections in livestock and poultry, serious complications, and great harm to livestock and poultry. Also do not have comparatively desirable therapeutic drug treating both symptoms and root causes on the market now. Through investigation and research on the domestic and international markets, it is found that the market is in urgent need of a drug that has a stable drug effect, good curative effect, high stability, and is easy to use, and has special effects on livestock and poultry respiratory infections with high incidence and serious complications. [0003] In the prior art, tylosin tartrate is a special antimicrobial drug for macrolides for animals, and it mainly has good effects on most Gram-positive bacteria...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K9/14A61P31/04A61P29/00A61K31/245A61K31/167A61K31/7036
Inventor 陈益德胡学全周可刚何丽花刘亚
Owner SICHUAN DERUNTONG BIOTECH
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