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Traditional Chinese medicine composite as well as product and application thereof

A technology for compositions and finished products, applied in the directions of pharmaceutical combinations, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc. Problems such as the role of early prevention or mid-term treatment of diabetic foot

Active Publication Date: 2012-08-15
SICHUAN SUNNYHOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the formula of this patent is unreasonable, the dosage of some main Chinese medicine raw materials is too small, and it is only used for the treatment of late gangrene. There is no pharmacological explanation of its mechanism of action

Method used

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  • Traditional Chinese medicine composite as well as product and application thereof
  • Traditional Chinese medicine composite as well as product and application thereof
  • Traditional Chinese medicine composite as well as product and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: Tablet preparation of the composition of the present invention

[0036] Take the following traditional Chinese medicine raw materials: Astragalus 28g, Mulberry 14g, Salvia 12g, Angelica 8g, Yinhuateng 22g, Ligusticum chuanxiong 14g, Panax notoginseng 4g, Caulis Spatholobus 22g, Polygonum multiflorum 18g, Gallinarum 14g, add 8 and 6 times respectively Measure water and decoct twice, each for 1.5 and 1 hour, combine the decoction, filter, concentrate to a clear paste with a relative density of 1.20, add ethanol to make the alcohol content reach 65%, let stand for 24 hours, filter, and filtrate Recover ethanol under reduced pressure, centrifuge, concentrate, spray dry, add starch to granulate, press into 15 tablets, and coat to obtain. Oral 3 times a day, 5 tablets each time.

Embodiment 2

[0037] Embodiment 2: the paste of composition of the present invention or plaster health product preparation

[0038] Get the following weight of Chinese medicine raw materials: Astragalus 22g, mulberry 10g, Salvia miltiorrhiza 6g, Angelica 6g, Yinhuateng 38g, Caulis Spatholobus 38g, Polygonum multiflorum 12g, litchi core 16g, Chinese yam 30g, licorice 5g, pulverize, pass through a 60-mesh sieve, and obtain The powder is added with preservatives, wetting agents and adhesives, sealed and packaged into 1 bag, and the health product for improving the symptoms of diabetic foot or peripheral neuritis can be obtained. Just before use, unpack the package and apply to the affected area.

Embodiment 3

[0039] Embodiment 3: the injection preparation of composition of the present invention

[0040] Take the following traditional Chinese medicine raw materials: Astragalus 38kg, Mulberry 15kg, Salvia miltiorrhiza 14kg, Angelica sinensis 14kg, Yinhuateng 32kg, add 8 and 6 times the amount of water for injection and decoct for 1.5 and 1 hour respectively, combine the decoction, filter, and concentrate the filtrate To a relative density of 1.15, add ethanol to make the alcohol content reach 60%, let stand for 24 hours, filter, and recover ethanol from the filtrate under reduced pressure, then concentrate to a relative density of 1.20, add ethanol to make the alcohol content reach 80%, let stand for 48 hours , filter, recover ethanol and centrifuge, take the supernatant, add the excipients required for injection, mix well, adjust the pH value to 5.0-7.0, add water for injection to 10000ml, filter, fill, sterilize, and get ready. Inject once a day, 10ml each time.

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Abstract

The invention relates to a traditional Chinese medicine composite as well as a product and an application of the traditional Chinese medicine composite. The composite comprises the following traditional Chinese medicine raw materials in parts by weight: 20-40 parts of Astragalus mongholicus and 10-20 parts of mulberry and also comprises one or several of the following traditional Chinese medicine raw materials in parts by weight: 5-15 parts of salviae miltiorrhizae, 5-15 parts of angelica sinensis, 10-20 parts of processed fleece-flower root, 5-15 parts of rhizoma chuanxiong and 1-5 parts of pseudo-ginseng. The traditional Chinese medicine composite has better actions on lowering sugar, lowering fat, improving a blood rheology index, reducing urine protein or improving the creatinine clearance rate and especially has the actions on protecting the vascular endothelial cell, alleviating the damage degree of the endarterium and the like, and therefore the traditional Chinese medicine composite can be prepared into oral administration or external application products used for treating or controlling renal damage, neuropathy around limbs, high blood fat, impotence, prostatic hyperplasia, diabetes mellitus and complications, such as diabetic foot, diabetic nephropathy and diabetic retinal inflammation, and has good protecting action on the liver, the kidney, the pancreas and the intestinal mucosa.

Description

technical field [0001] The invention relates to a composition, in particular to a composition prepared with traditional Chinese medicine as the main raw material. The invention also relates to preparations and uses of such compositions. Background technique [0002] Diabetes is an endocrine and metabolic disease whose etiology and pathogenesis are not yet fully understood. It is a chronic progressive systemic disease with a long course. In severe cases, ketoacidosis or other types of acute metabolic disorders may occur. Common complications include diabetic nephropathy, diabetic foot, retinopathy, hypertension, microvascular disease and neuropathy, etc. Therefore, diabetes is a disease that seriously endangers human health. Social surveys show that: with the aging of the world's population, diabetes has become a common and frequently-occurring disease, and its incidence is on the rise in industrially developed countries. Diabetes is a lifelong disease with complex etiology...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61K36/704A61K36/77A61K36/884A61K36/8945A61P1/16A61P1/18A61P3/06A61P3/10A61P5/50A61P9/10A61P9/14A61P13/08A61P13/12A61P15/10A61P17/02A61P25/02A61P43/00A61K35/37A61K35/57
Inventor 亓鲁光郭成辉王建波梁灏王晓玲
Owner SICHUAN SUNNYHOPE PHARM CO LTD
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