Renal failure treating Chinese medicinal preparation and preparation method thereof

Abstract

The invention discloses a renal failure treating Chinese medicinal preparation, which consists of heterophylly falsestarwort root, coptis root, rhizoma pinellinae praeparata, dried orange peel, indian buead, rhubarb, red-rooted salvia root, twotooth achyranthes root and the like. A preparation to a mobile phase is inspected with a high performance liquid chromatography method: the ratio of methanol to water is 45:55; a detection wavelength is 254 nanometers; the theoretical number of plates is more than or equal to 5000; and not less than 3.2mg of total alkaloids is contained in every 0.35g of berberine hydrochloride. A preparation method of the preparation comprises the following steps of: preparing materials, and preparing raw rhubarb powder from a part of the rhubarb; preparing rhubarb thick paste from a part of the rhubarb; preparing a medicament thick paste: preparing mixed thick paste; uniformly mixing the mixed thick paste with the raw rhubarb powder; preparing renal failure treating medicinal powder; preparing into a capsule, a tablet, an instant herbal medicine, powder and an oral liquid; and inspecting. A renal failure treating medicament provided by the invention has the advantages of higher chemical stability, stable product quality, higher content uniformity, very low content deviation, great increase in active ingredients, quick release of contents after the preparation is taken, high in-vivo utilization ratio and high absorbing rate.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a Shenshuaining traditional Chinese medicine preparation and a preparation method thereof. Background technique [0002] Chronic renal failure is the decline in renal function caused by various chronic kidney diseases. Due to the abnormal excretion and regulation of the kidneys, the extreme disturbance of water, electrolyte and acid-base balance, as well as the retention of nitrogen metabolites in the body, CRF is extremely harmful to people's health. One of the diseases is one of the key project topics that the medical field urgently needs to solve. At present, hemodialysis, peritoneal dialysis and kidney transplantation are mainly used in the treatment of CRF at home and abroad. The cost is high and it is a heavy burden on society, family and individual. Traditional Chinese medicine plays an important role in delaying the progress of CRF, r...

AI Technical Summary

Problems solved by technology

It often happens that the same amount of raw materials and the same preparation process are used in production, but the active ingredients in the produced products are different, making it difficult to accurately control the active ingredients in traditional Chinese medicine preparations

The raw material medicine is directly molded after crushing, so that the active ingredients in the raw material of the product are low, the chemical properties and quality of the medicine are unstable, the absorption rate is low, the dosage is large, the product volume is large, and the medicine needs to occupy a large amount of time in transportation and storage. space

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