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Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications

A composition and a technology for diabetes, applied in the field of medicine, can solve the problems such as that the complications of diabetes are not effectively suppressed and the like

Active Publication Date: 2012-04-04
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional diabetes treatment focuses on changes in blood sugar and blood pressure, so diabetic complications have not been effectively suppressed

Method used

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  • Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications
  • Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications
  • Application of traditional Chinese medicinal composition in preparation of medicament for controlling diabetes complications

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0145] Add 6 times of water to 50 g of Herba Asarum, extract by steam distillation for 6 hours, filter, collect the volatile oil, and collect the filtrate in another device; add 3 times of β-cyclodextrin to the volatile oil, add 2 times of water, grind for 30 minutes, and dry at low temperature (50°C). Grind into fine powder and sieve for later use; 100 g of red ginseng was reflux extracted with 75% ethanol three times, each time for 1.5 hours, filtered, and the filtrates were combined to recover ethanol. Add 250g of epimedium, 750g of saline roasted psoralen, 250g of medlar, 250g of ephedra, 375g of salvia miltiorrhiza, 250g of leech, etc., add 10 times of water, decoct three times, 1 hour each time, and combine the decoction with the above two filtrates , filtered, the filtrate was concentrated under reduced pressure (40° C.) to a clear paste with a relative density of 1.20, the above-mentioned β-cyclodextrin inclusion compound was added, and packed into capsules to obtain 10...

Embodiment 2

[0147] Add 6 times of water to 50 g of Herba Asarum, extract by steam distillation for 6 hours, filter, collect the volatile oil, and collect the filtrate in another device; add 3 times of β-cyclodextrin to the volatile oil, add 2 times of water, grind for 30 minutes, and dry at low temperature (50°C). Grind into fine powder and sieve for later use; 100 g of red ginseng was reflux extracted with 75% ethanol three times, each time for 1.5 hours, filtered, and the filtrates were combined to recover ethanol. Add 250g of epimedium, 750g of saline roasted psoralen, 250g of medlar, 250g of ephedra, 375g of salvia miltiorrhiza, 250g of leech, etc., add 10 times of water, decoct three times, 1 hour each time, and combine the decoction with the above two filtrates , filter, and concentrate the filtrate under reduced pressure (40°C) to a clear paste with a relative density of 1.20, add the above-mentioned β-cyclodextrin inclusion complex, compressible starch, sodium carboxymethylcellulos...

Embodiment 3

[0149] Add 6 times of water to 50 g of Herba Asarum, extract by steam distillation for 6 hours, filter, collect the volatile oil, and collect the filtrate in another device; add 3 times of β-cyclodextrin to the volatile oil, add 2 times of water, grind for 30 minutes, and dry at low temperature (50°C). Grind into fine powder and sieve for later use; 100 g of red ginseng was reflux extracted with 75% ethanol three times, each time for 1.5 hours, filtered, and the filtrates were combined to recover ethanol. Add 250g of epimedium, 750g of saline roasted psoralen, 250g of medlar, 250g of ephedra, 375g of salvia miltiorrhiza, 250g of leech, etc., add 10 times of water, decoct three times, 1 hour each time, and combine the decoction with the above two filtrates , filtered, the filtrate was concentrated under reduced pressure (40°C) to a clear paste with a relative density of 1.20, the above-mentioned β-cyclodextrin inclusion compound was added, dried and pulverized into fine powder a...

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Abstract

The invention relates to a novel application of a traditional Chinese medicinal composition in the preparation of a medicament for controlling diabetes complications. The prescription contains, by weight, 100 parts of red ginseng, 250 parts of epimeddium, 750 parts of brine-heated Psoralea corylifolia, 250 parts of wolfberry, 250 parts of ephedra stem, 50 parts of Asarum Herb, 375 parts of red sage root and 250 parts of leech. The dosage form comprises pills, a particulate agent, hard capsules, soft capsules, tablets, dropping pills or an oral liquid. The invention aims to provide a novel treatment application of the pharmaceutical composition, enlarge the clinic application range of the pharmaceutical composition and avoid waste of good drug resources.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a traditional Chinese medicine composition in the preparation of medicines for preventing and treating diabetic complications. Background technique [0002] Diabetes is a common chronic disease. With the improvement of people's living standards, the aging population and the increase in the incidence of obesity, the incidence of diabetes is increasing year by year. According to the report of Jia Chunbao Diabetic Foot Research Institute: At present, the incidence of diabetes in my country has reached more than 3%, and the number of diabetic patients has reached 45 million, and it is increasing at a rate of about 1.5 million per year. People didn't pay much attention to diabetes at first, and then complications appeared, and the consequences were quite serious. Foot disease, kidney disease, eye disease, encephalopathy, heart disease, skin disease, sexual dysf...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P1/02A61P3/10A61P9/00A61P9/10A61P13/12A61P15/08A61P17/00A61P17/04A61P25/02A61P29/00A61K35/62
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA
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