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Toothpaste containing dencichine and preparation method thereof

A technology of notoginseng and toothpaste, applied in dentistry, pharmaceutical formulations, cosmetic preparations, etc., to achieve significant curative effect, significant gum bleeding and pain, and eliminate oral odor

Active Publication Date: 2012-03-21
YUNNAN PHYTOPHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

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  • Toothpaste containing dencichine and preparation method thereof
  • Toothpaste containing dencichine and preparation method thereof
  • Toothpaste containing dencichine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Raw material ratio: (weight percentage, the same below)

[0038] Notoginsenoside 0.2%

[0039] Panax notoginseng 0.01%

[0040] Dicalcium Phosphate 50% (abrasive)

[0041] Silica 2% (abrasive)

[0042] Glycerin 18% (humectant)

[0043] Polyethylene glycol 1% (humectant)

[0044] Sodium pyrophosphate 0.2% (stabilizer)

[0045] Xanthan Gum 0.2% (Thickener)

[0046] Sodium Hydroxymethyl Cellulose 0.1% (Binder)

[0047] Sorbitol 10% (humectant, detergent, binder, sweetener)

[0048] Zinc Citrate 0.05% (fights plaque and gingivitis)

[0049] Sodium Saccharin 0.1% (Sweetener)

[0050] Sodium Lauryl Sulfate K12 1% (foaming agent)

[0051] Ethylparaben 0.1% (preservative)

[0052] Propylparaben 0.01% (preservative)

[0053] Fragrance 0.1% (flavor enhancer)

[0054] water to 100%

[0055] Preparation method:

[0056] 1) Dissolve notoginseng saponins and notoginseng in water to obtain an aqueous solution, and set aside;

[0057] 2) Dissolve sodium pyrophosphate in...

Embodiment 2

[0064] Notoginsenoside 0.8%

[0065] Panax notoginseng 0.3%

[0066] Dicalcium Phosphate 46% (abrasive)

[0067] Silica 3% (abrasive)

[0068] Glycerin 8% (humectant)

[0069] Polyethylene glycol 4% (humectant)

[0070] Sodium pyrophosphate 0.5% (stabilizer)

[0071] Xanthan Gum 0.6% (Thickener)

[0072] Sodium hydroxymethylcellulose 0.3% (binder)

[0073] Sorbitol 14% (humectant, detergent, binder, sweetener)

[0074] Zinc Citrate 0.5% (fights plaque and gingivitis)

[0075] Sodium Saccharin 0.25% (Sweetener)

[0076] Sodium Lauryl Sulfate K12 2.5% (foaming agent)

[0077] Ethylparaben 0.2% (preservative)

[0078] Propylparaben 0.05% (preservative)

[0079] Fragrance 1.3% (flavor enhancer)

[0080] water to 100%

[0081] Preparation method is the same as embodiment 1.

Embodiment 3

[0083] Notoginsenoside 1.2%

[0084] Panax notoginseng 1.0%

[0085] Dicalcium Phosphate 25% (abrasive)

[0086] Silica 8% (abrasive)

[0087] Glycerin 6% (humectant)

[0088] Polyethylene Glycol 7% (humectant)

[0089] Sodium pyrophosphate 1.0% (stabilizer)

[0090] Xanthan Gum 1.5% (Thickener)

[0091] Sodium Hydroxymethyl Cellulose 2.0% (Binder)

[0092] Sorbitol 25% (humectant, detergent, binder, sweetener)

[0093] Zinc Citrate 2% (fights plaque and gingivitis)

[0094] Sodium Saccharin 1% (Sweetener)

[0095] Sodium Lauryl Sulfate K12 5% (foaming agent)

[0096] Ethylparaben 0.5% (preservative)

[0097] Propylparaben 0.5% (preservative)

[0098] Fragrance 3% (flavor enhancer)

[0099] water to 100%

[0100] Preparation method is the same as embodiment 1.

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Abstract

The invention relates to toothpaste containing dencichine, which is characterized in that the toothpaste is prepared by adding arasaponin and dencichine into a toothpaste matrix, wherein the weight percent of the arasaponin is 0.2-1.2% and the weight percent of the dencichine is 0.01-1.0%. The toothpaste according to the invention can kill pyococcus, candida albicans, staphylococcus aureus, anaerobic bacteria and other pathogens which can cause gingivitis, periodontitis, canker sores, halitosis, ngival hamorrhage, caries and other symptoms in the oral cavity and eliminate the peculiar smell in the oral cavity. The effective rate for the gingivitis and the ngival hamorrhage achieves 94.6%; and the effective rate for the canker sores achieves 89%, and the efficacy is significant. The toothpaste has no toxicity or side effects, is safe to use and can prevent drug resistance. The toothpaste has significant efficacy for the gingivitis, the ngival hamorrhage, the canker sores and the like. The hemostatic effect of the toothpaste is well promoted. Sanchi extract and the dencichine are simultaneously used in the toothpaste, thereby enabling the effects of relieving pain and preventing thegingivitis, the ngival hamorrhage and the pain of the toothpaste to be more significant.

Description

technical field [0001] The invention relates to an oral care article, in particular to a toothpaste containing notoginseng and a preparation method thereof. Background technique [0002] Panax notoginseng is Araliaceae plant Panax notoginscng (Burk.) F. H. Chen's dry root, also known as Shanqi, Jinbuhuan, Tianqi and so on. Mainly produced in Yunnan, Guangxi and other places, wild or cultivated. Its nature is sweet, slightly bitter, warm. Mainly enters the liver, stomach, and large intestine meridians, and has the functions of "removing blood stasis and stopping bleeding, reducing swelling and relieving pain". In terms of its function, "Compendium of Materia Medica" says: "Stop bleeding, disperse blood, and calm pain. For those who have wounds from golden blade arrows, sores from falling sticks, and bleeding that does not stop, chew it and apply it, or mix it at the end, and the blood will stop. Also Mainly vomiting blood, bleeding, bloody dysentery, metrorrhagia, menstr...

Claims

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Application Information

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IPC IPC(8): A61K8/86A61K8/63A61K8/44A61Q11/00A61P31/04A61P31/10A61P1/02
Inventor 李俊苏莎罗姗姗杨立民
Owner YUNNAN PHYTOPHARML
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