Preparation method of total flavone from natural plant

Abstract

The invention provides a preparation method of the total flavone from the natural plant, belonging to the technical field of the plant. The method comprises the steps of: taking the aeschynanthus moningeriae as a raw material, and taking alcohol containing water as dissolvent to extract the tissue in a breaking way; filtering in a pumping way, merging filter liquor, and recovering the dissolvent by means of flashing and concentrating; and separating and enriching the obtained concentrated liquor by macroporous absorption resin, performing gradient elution on the alcohol containing water, merging the eluent of the alcohol containing water with a certain proportion to recover the dissolvent by means of flashing and concentrating, and continuously performing the vacuum drying on the solvent to obtain dried powder so as to obtain the total flavone extractive of the aeschynanthus moningeriae. The preparation method is simple in technology, advanced in extraction and concentration technology, convenient in operation, low in cost, green and high-efficiency, so that the total flavone content in the extractive is 32.27%-43.69%, the extracting rate is 8.56%-13.56%, and the transferring rate is as high as 72.33%-84.45%. The preliminary extracorporeal bioactivity test shows that the specific total flavone extractive of the aeschynanthus moningeriae has a certain antibacterium activity and antioxidation activity.

Description

technical field [0001] The invention belongs to the technical field of plants, in particular to a preparation method of total flavonoids derived from natural plants. Background technique [0002] Natural flavonoids are a class of important biologically active substances that widely exist in the plant kingdom. They are widely found in plants of different families and genera, mainly in Rutaceae, Lamiaceae, Fabaceae, Umbelliferae, Ginkgoceae and Compositae. middle. According to research, about 20% of Chinese herbal medicines contain flavonoids, which shows the abundance of its resources. Flavonoids can be obtained directly from food or extracted from plants rich in flavonoids. It can not only be used as a drug for preventing and treating cardiovascular and cerebrovascular diseases, but also has obvious anti-lipid peroxidation, anti-aging, and scavenging free It has physiological activities such as lowering blood fat, lowering cholesterol, lowering blood sugar, anti-cancer, an...

AI Technical Summary

Problems solved by technology

The chemical components contained in the plants of this family are mainly flavonoids, phenylethyl alcohols, quinones and terpenes, etc., which have significant antibacterial, anti-oxidant, anti-viral, anti-inflammatory, expectorant and cough-relieving effects, but for mans There are no reports on the research on the plant of the genus Trichosanthes - Miscanthus safflower, whether it is basic or development and application research

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