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Preparation method of traditional Chinese medicine ointment

A technology of traditional Chinese medicine ointment and ointment, which is applied in the direction of medical formula, medical preparations containing active ingredients, and ointment delivery. The quality of the ointment is uniform and controllable, and the effect of reducing pesticide residues

Inactive Publication Date: 2010-12-22
上海泰坤堂中医医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] One object of the present invention is to provide a preparation method of traditional Chinese medicine ointment, which effectively solves the problems of pesticide residues, easy destruction of drug components, short storage time and easy deterioration of medicine, inaccurate dosage and poor drug effect in the traditional ointment preparation process.
[0017] Another object of the present invention is to provide a preparation method of traditional Chinese medicine ointment, especially for the preparation of ointment containing animal medicinal materials, Class A medicinal materials and precious medicinal materials, which not only solves the problems of pesticide residues, easy destruction of medicinal ingredients, and drug residues in the traditional ointment preparation process. The storage time is short and perishable, the dosage is inaccurate, and the effect of taking medicine is poor. It also solves the waste of precious medicinal materials in the ointment caused by improper decoction, and ensures the maximum efficacy of the medicinal materials.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] The preparation of embodiment 1 ointment

[0059] The Chinese medicinal materials Angelica 100g, Paeoniae Alba 120g, Poria cocos 120g, Codonopsis 150g, Toon root bark 120g, Celosia 60g, Fried Atractylodes macrocephala 120g, Rosaceae 150g, Dodder 150g, Ligustrum lucidum 150g, Eclipta 300g, Astragalus 300g, Mulberry 150g, Agrimony 120g, Morinda officinalis 100g, Rubia 45g, Ocher 100g, Morinda officinalis 100g, Caulis 300g, Albizia juniper 300g, Polygala 60g, Cistanche 100g, Whole Trichosanthes 120g, Tangerine peel 60g, Jiaozha 150g of koji (each), 30g of amomum, 150g of scrophulariaceae and 60g of bergamot are mixed, and the water with a weight ratio of 10 times is used for washing.

[0060] Soak in the container for 11 hours after washing, so that the medicinal materials are fully infiltrated by water. Then decoct under normal pressure, using the traditional decocting process of decocting first and then decocting. After decocting, let it settle for 10 minutes, filter ou...

Embodiment 2

[0061] The preparation of embodiment 2 ointment

[0062] Chinese medicinal materials astragalus 150g, codonopsis 150g, angelica 90g, chuanxiong 90g, red peony root 90g, rehmannia glutinosa 100g, peach kernel 90g, motherwort 150g, achyranthes bidentata 90g, milletus spatholobus 120g, cassia twig 60g, Patrinia 150g, knotweed 150g, 60g Passepartout, 90g saponins, 60g Cyperus, 30g Asarum, 60g Fritillaria, 100g Salvia, 90g Curcuma, 90g Polyporus 90g, 60g Alisma, 60g Zelan, 200g rice kernels, 90g Xianlingpi, Mix asparagus 90g, Magnolia officinalis 60g, Muxiang 60g and Dabupi 60g, and wash with water with a weight ratio of 10 times.

[0063] Soak in the container for 11 hours after washing, so that the medicinal materials are fully infiltrated by water. Then decoct under normal pressure, using the traditional decocting process of decocting first and then pouring. After decocting, let it settle for 10 minutes, filter out the medicinal liquid and concentrate it under reduced pressure....

Embodiment 3

[0064] The detection of embodiment 3 ointment

[0065] The ointment prepared in Example 2 was divided into packages of 25 ml per bag, and placed at a temperature of 42° C. for 3 months. According to the "Pharmacopoeia of the People's Republic of China" 2005 edition, the microbial limit standard of oral administration preparations was tested. The results were: the number of bacteria: no more than 1000 per 1g; the number of mold and yeast: no more than 100 per 1g; Escherichia coli was not detected per 1g.

[0066] The ointment that embodiment 2 is made is divided into the packing of every bag 25ml, and room temperature is placed 12 months. According to the "Pharmacopoeia of the People's Republic of China" 2005 edition, the microbial limit standard of oral administration preparations was tested. The results were: the number of bacteria: no more than 1000 per 1g; the number of mold and yeast: no more than 100 per 1g; Escherichia coli was not detected per 1g.

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Abstract

The invention relates to a preparation method of a traditional Chinese medicine ointment, which comprises the steps of pretreatment of traditional Chinese medicine materials, soaking of the medicine materials, normal-pressure decoction, depressurized concentration, ointment extracting, subpackaging and the like, wherein the medicine materials should be flushed with water of which the weight is 0.2-100 times more than that of the medicine materials to reduce pesticide residues; after the normal-pressure decoction, the medicine materials should be kept in an closed environment for precipitation for 5-60 minutes; and in the ointment extracting process, the density of the ointment should be strictly controlled to be within the range of 1.1mg / ml-1.4mg / ml. When the ointment contains animal medicine materials, class A medicine materials and precious medicine materials, the animal medicine materials, the class A medicine materials and the precious medicine materials should be added to the ointment after being extracted or be directly swallowed after superfine pulverization. The invention effectively solves the problems of pesticide residue and easy destruction of medicine components in the traditional ointment preparation process as well as short storage time, easy deterioration, inaccurate dosage, poor medicine effect and the like of the medicament. For the animal medicine materials, the class A medicine materials and the precious medicine materials used in the ointment, the invention also avoids the waste of these medicine materials as a result of incorrect decoction, and ensures the efficacy of the medicine materials to the greatest extent.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical preparation, in particular to a preparation method of a traditional Chinese medicine ointment. The prepared ointment has uniform and controllable quality. Background technique [0002] Ointment, also known as ointment, is named after its dosage form, and belongs to one of the eight dosage forms of pills, powder, ointment, pill, wine, dew, soup and tablet in traditional Chinese medicine. In the theory of traditional Chinese medicine, ointment is a kind of patented medicine with comprehensive functions of advanced nutrition, nourishment, treatment and prevention. It is a thick semi-liquid or jelly-like dosage form based on a large-scale compound decoction, with different prescriptions established according to people's different constitutions and different clinical manifestations. [0003] Chinese invention patent application 200410033913.X discloses an ointment for treating fractures and ...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K35/32A61K35/36A61K35/50A61K35/56A61K35/62A61K35/64A61K36/889A61K36/896A61K36/8966A61K9/06A61K9/70A61K35/586A61K35/60A61K35/646A61K35/648
Inventor 武大圣
Owner 上海泰坤堂中医医院有限公司
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