Process for extracting diosgenine from turmeric by catalytic hydrolysis method

Abstract

The invention discloses a process for extracting diosgenine from turmeric by a catalytic hydrolysis method, which comprises the following steps of: crushing a turmeric raw material subjected to cellulose and starch removal to prepare a refined raw material; adding 0.02 to 0.02mol / L aqueous solution of catalyst into the refined raw material, heating and pressurizing to perform catalytic hydrolysis, and obtaining hydrolysis products, wherein the catalyst is one of transition metal salt, bipyridyl chelate of the transition metal salt, and tri(2-picolyl) amine complex of the transition metal salt, or a mixture of the transition metal salt and the bipyridyl chelate of the transition metal salt, or a mixture of the transition metal salt and the tri(2-picolyl) amine complex of the transition metal salt; and finally, dissolving the hydrolysis products with an organic solvent, extracting and crystallizing to obtain the diosgenine. The diosgenine is extracted from the turmeric by the catalytic hydrolysis method, the generation of a great deal of acid wastewater is avoided, and the environment is protected. Moreover, the catalyst in the process is a common compound, the process conditions are easily met, and the process can be promoted and applied.

Description

technical field [0001] The invention relates to a process for extracting diosgenin, in particular to a process for extracting diosgenin from yellow ginger by catalytic hydrolysis. Background technique [0002] Diosgenin, commonly known as diosgenin, has the functions of hemolysis, hypolipidemic, antibacterial, and anti-inflammatory effects. It is also an important pharmaceutical and chemical raw material for the synthesis of steroid hormones and steroidal contraceptives. Among them, steroid hormone drugs are widely used, and are often used in the treatment of rheumatoid arthritis, cardiovascular and cerebrovascular diseases, etc., and steroidal contraceptives play an important role in the implementation of the basic national policy of family planning in my country. In addition, in recent years, many scholars at home and abroad have reported that dioscin also has anti-tumor effects, and some scholars have reported that the active ingredient of Di'ao Xinxuekang Capsules, a Ch...

AI Technical Summary

Problems solved by technology

But this production process mainly has following problems: the one, the direct hydrolysis of raw material turmeric is not thorough, and the existence of a large amount of cellulose and starch interferes with hydrolysis, so the yield of diosgenin is low; Repeated washing, not only the consumption of water is large, but also the loss of semi-finished products in the washing process is serious; the third is the large amount of waste water discharge, serious environmental pollution

This process makes full use of the starch and glucose in yam crops such as turmeric, and ferments them to produce ethanol, which saves costs, but still produces acidic wastewater, which has a certain degree of pollution to the environment.