Effervescent tablet of plant growth regulator composition and preparation method thereof
A plant growth regulator and growth regulator technology, applied in the directions of plant growth regulators, plant growth regulators, botanical equipment and methods, etc., can solve phytotoxicity, agricultural production losses, and accurate stability of active ingredients in water preparation products Quantitative difficulties and other problems, to achieve the effect of rapid disintegration, sufficient dissolution, and reducing the occurrence of phytotoxicity
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Embodiment 1
[0036] Example 1 Preparation of 0.2% diethyl diethyl ethyl methylpiperium effervescent tablet
[0037] The former drug diethyl hexanoate selects the 98.0% diethyl hexanoate former powder produced by Henan Zhengzhou Zhengshi Chemical Co., Ltd., and the former drug methylpiperium selects the 97.0% methylpiperium former powder produced by Jiangsu Changzhou Jiangnan Pesticide Factory (the following examples are the same) .
[0038] The selection and proportioning of the original drug and auxiliary agents are: 0.102 parts by mass of 98% diethyl hexanoate original drug (0.1 part by mass of pure), 0.104 parts by mass of 97.0% methylpiperium original drug (0.1 part by mass of pure), water blocking agent 0.1 parts by mass of diatomaceous earth, 30.0 parts by mass of acid effervescent agent oxalic acid, 30.0 parts by mass of alkaline effervescent agent sodium bicarbonate, 3.0 parts by mass of binder lactose, 5.0 parts by mass of glidant talc, 31.694 parts by mass of filler white carbon ...
Embodiment 2
[0050] Example 2 Preparation of 20% diethyl aminoethyl hexanoate mepiperium effervescent tablet
[0051] The selection and proportioning of the original drug and auxiliary agents are: 15.3 parts by mass of 98% diethyl hexanoate (15.0 parts by mass in pure form), 5.2 parts by mass of 97.0% methylpiperium original drug (5.0 parts by mass in pure form), water blocking agent 5.0 parts by mass of calcium carbonate, 10.0 parts by mass of acidic effervescent agent citric acid, 10.0 parts by mass of alkaline effervescent agent potassium bicarbonate, 3.0 parts by mass of binder carboxymethyl cellulose, 5.0 parts by mass of glidant calcium stearate , 46.5 parts by mass of filler kaolin.
[0052] Based on the preparation of a 10 kg sample, the dosage of each component is calculated and weighed according to the above proportions. Prepared by wet granulation and then tabletting, the method is as follows:
[0053] (1) After drying 1.53 kg of diethyl hexanoate and 0.52 kg of methylpiperium...
Embodiment 3、27
[0061] Embodiment 3, the preparation of 27.5% diethyl aminoethyl methylpiperium effervescent tablet
[0062] The selection and proportioning of the original drug and auxiliary agents are: 2.6 parts by mass of 98% diethyl ethyl hexanoate (2.5 parts by mass in pure form), 25.8 parts by mass of 97.0% methylpiperium technical product (25.0 parts by mass in pure form), water blocking agent 10.0 parts by mass of calcium hydrogen phosphate, 12.0 parts by mass of acid effervescent agent tartaric acid, 8.0 parts by mass of alkaline effervescent agent potassium carbonate, 3.0 parts by mass of binder polyethylene glycol, 3.0 parts by mass of glidant magnesium stearate, filler 35.6 parts by mass of bentonite.
[0063] Calculate and weigh the dosage of each component according to the above proportioning ratio. It is prepared by the direct dry compression method, and the specific process is the same as in Example 1.
[0064] The weight of each tablet of the prepared effervescent tablet is...
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