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Traditional Chinese medicine composition for treating thrombophlebitis and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of not effectively destroying the cell structure of animal medicinal materials, affecting the dissolution, release and absorption of medicinal substances, and reducing the bioavailability of medicinal medicinal substances, so as to save resources of Chinese medicinal materials , reduce drug dosage, increase the effect of bioavailability

Active Publication Date: 2010-01-06
LUNAN HOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1) The obtained medicinal powder cannot be fully sieved at one time, and different parts of animal medicinal materials have different degrees of difficulty in crushing, which requires multiple sieving and grinding, and eventually produces particles that do not meet the fineness requirements (less than 200 mesh) The tailings do not meet the theoretical requirements of traditional Chinese medicine, which emphasizes the use of all components of medicinal materials used in prescriptions, and also affect the uniformity of product quality;
[0006] 2) Due to the impact of long-term mechanical heat energy during the crushing process, the protein, polypeptide and thermally unstable components in animal medicinal materials are destroyed;
[0007] 3) It cannot effectively destroy the cell structure of animal medicinal materials, affect the dissolution, release and absorption of medicinal substances, and reduce the bioavailability of medicinal medicinal substances in the human body, etc.

Method used

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  • Traditional Chinese medicine composition for treating thrombophlebitis and preparation method thereof
  • Traditional Chinese medicine composition for treating thrombophlebitis and preparation method thereof
  • Traditional Chinese medicine composition for treating thrombophlebitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1: Preparation of superfine powder vein dredging particles

[0043] A. After cleaning, washing, sterilizing and drying the three kinds of animal medicines of leeches, centipedes and scorpions, they are ultrafinely pulverized by the optimal ultrafine pulverizer unit, so that the average particle size of the medicine powder is less than 1 μm;

[0044] B extraction concentration and drying process:

[0045] Add water to extract the volatile oil of honeysuckle, herb, scrophulariaceae, angelica, and white peony root, decoct the dregs with astragalus, cortex phellodendron, coix seed, and licorice together with water to extract, filter the water extract, concentrate, add ethanol to dissolve and extract, and then concentrate into water extract;

[0046] C granulation is divided into three granulation methods according to the different states of the extract after extraction. One is to mix and granulate leech, centipede, scorpion superfine powder with water extract an...

Embodiment 2

[0047] Embodiment 2: Preparation of superfine powder vein dredging particles

[0048] A. After cleaning, washing, sterilizing and drying the leeches, centipedes and scorpions, the three animal medicines are ultrafinely pulverized by the optimal ultrafine pulverization unit, so that the average particle size of the medicine powder is between 1-5 μm;

[0049] B extraction concentration and drying process: see embodiment 1

[0050] C preparation process: see embodiment 1

Embodiment 3

[0051] Embodiment 3: Preparation of superfine powder vein dredging particles

[0052] A. After cleaning, washing, sterilizing and drying the three kinds of animal medicines of leech, centipede and scorpion, they are ultrafinely pulverized by the optimal ultrafine pulverization unit, so that the average particle size of the medicine powder is between 5-10 μm;

[0053] B extraction concentration and drying process: see embodiment 1

[0054] C preparation process: see embodiment 1

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Abstract

The invention discloses a traditional Chinese medicine composition for treating thrombophlebitis. The invention also discloses a preparation method of the traditional Chinese medicine composition. The preparation method of the traditional Chinese medicine composition comprises the following steps: taking three kinds of animal class medicinal powder of leech, centipede and scorpio which are processed by a superfine pulverization technique and have the average particle diameter smaller than the fineness of 75mum and medicinal materials of which volatile oil is extracted, adding water firstly, extracting the volatile oil, taking the medicinal materials after extracting the volatile oil and other medicinal materials which are extracted by using the water, adding the water, decocting, extracting, and preparing water extractive paste by a water extract through filtration, concentration, ethanol transfer dissolution and concentration.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating thrombophlebitis (including superficial thrombophlebitis and deep vein thrombosis), and also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] Thrombophlebitis refers to acute non-suppurative inflammation in the venous lumen, accompanied by thrombosis. It is a common vascular thrombotic disease, and the lesions mainly involve the superficial and deep veins of the extremities. Thrombosis can cause inflammation, and inflammation can also cause thrombus, and the two are mutually causal. [0003] Thrombophlebitis is a common and difficult clinical disease. The disease is still in the stage of exploration and research at home and abroad. Antibiotics and alkylating agents can damage the venous intima to varying degrees, leading to thrombosis; anticoagulant therapy can...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P7/02A61P9/14A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 赵志全苏瑞强
Owner LUNAN HOPE PHARM CO LTD
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