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Skin physiology repair liquid and preparation method thereof

A repair liquid and physiological technology, applied in skin diseases, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as the advent of chitosan products, improve the body's immunity, prevent skin diseases, and inhibit elastin Degradation effect

Inactive Publication Date: 2009-10-21
DALIAN POLYTECHNIC UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is no report on the use of chitosan in the application of facial repair and the emergence of corresponding products

Method used

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  • Skin physiology repair liquid and preparation method thereof
  • Skin physiology repair liquid and preparation method thereof
  • Skin physiology repair liquid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: the preparation of skin repair liquid

[0044] (1) Preparation of composite chitosan solution: first 6g chitosan is dissolved in 2% citric acid 100g aqueous solution, the temperature is raised to 100° C., the boiling state is distilled back for 2 hours, cooled to 70° C. after vacuum concentration, suction filtration to remove impurities, Add 10 g of water-soluble chitosan oligosaccharides, 5 g of chitosan hydrochloride and 9 g of carboxymethyl chitosan to the filtrate at a temperature lower than 50° C. and filter again to obtain 115 g of complex chitosan solution.

[0045] (2) Preparation of traditional Chinese medicine extract: take the amount of plants according to the following mass percentages:

[0046] Coptis 0.5, Cnidium 1.5, Scutellaria baicalensis 1.5, Rosemary 2, Sophora flavescens 2, Bitter beans 2,

[0047] Mulberry leaf 1.5, snow lotus 0.05, propolis 0.05, ultrapure water 88.9.

[0048]Add 111g of plants to 889g of ultrapure water and soak fo...

Embodiment 2

[0050] Embodiment 2: the preparation of skin repair liquid

[0051] (1) Preparation of composite chitosan solution: first dissolve 3g chitosan in 110g aqueous solution of 8% citric acid, heat up to 100°C, return to boiling state for 2 hours, cool to 70°C after vacuum concentration, and suction filter To remove impurities, add 6g water-soluble chitosan oligosaccharide, 3g chitosan hydrochloride and 5g carboxymethyl chitosan to the filtrate at a temperature lower than 50°C, and filter again to obtain 114g composite chitosan solution.

[0052] (2) Preparation of traditional Chinese medicine extract: take the amount of plants according to the following mass percentages:

[0053] Coptis 1, Cnidium 2, Scutellaria baicalensis 3, Rosemary 4, Sophora flavescens 5, Bitter beans 2,

[0054] Mulberry leaf 1.5, snow lotus 0.05, propolis 0.05, ultrapure water 81.4.

[0055] Add 186g of plants to 814g of ultrapure water to soak for 24 hours, fully back-distill at 100°C for 2 hours, concent...

Embodiment 3

[0057] Embodiment 3: the preparation of skin repair liquid

[0058] (1) Preparation of composite chitosan solution: first 4g chitosan is dissolved in 90g aqueous solution of 3% citric acid, the temperature is raised to 100°C, the boiling state is distilled back for 2 hours, cooled to 70°C after vacuum concentration, and removed by suction filtration Miscellaneous, the filtrate was added 5g water-soluble oligochitosan, 3g chitosan hydrochloride and 5g carboxymethyl chitosan at a condition lower than 50°C, and suction filtered again to remove impurities to obtain 93g complex chitosan solution.

[0059] (2) Preparation of traditional Chinese medicine extract: take the amount of plants according to the following mass percentages:

[0060] Coptis 0.5, Cnidium 1.0, Skullcap 1.5, Rosemary 4.0, Sophora 3.0, Sophora 1.0, Mulberry leaf 1.5, Saussurea 2.0, Propolis 2.5, Ultrapure water 83.0.

[0061] Add 170g of plants to 830g of ultrapure water and soak for 24 hours, fully back-distill...

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Abstract

The invention discloses skin physiology repair liquid and a preparation method thereof. The skin physiology repair liquid is prepared by confecting and concentrating composite chitosan solution, gelatin, glycerin and Chinese herb extraction liquid; wherein, the composite chitosan solution is prepared by concentrating chitosan, water soluble low-molecular weight chitosan, chitosan hydrochloride and carboxymethyl chitosan, which are dissolved in diluted citric acid; the Chinese herb extraction liquid is extracted from coptis chinensis, fructus cnidii, radix scutellariae, rosemary, lightyellow sophora root, sophora alopecuroides, mulberry leaf, snow lotus and propolis. The invention achieves the effective rate of 89% in the first course of treatment of blain spots, cutaneous pruritus, contact dermatitis, allergic prurigo and spots and the effective rate of 95% in the second course of treatment. Antibacterial effects on gonococcus, staphylococcus aureus, colon bacillus and white cocci in laboratories excel the antibacterial effects of the commonly-used product Jieeryin lotion. The skin physiology repair liquid achieves the cure rate of 95% in the first course of treatment of gynecological leucorrhoea peculiar smell, vagina pruritus, congestion of vagina mucosa and vulva peculiar smell and the cure rate of 100% in the second course of treatment.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and its main components relate to plant extracts derived from chitosan and Chinese herbal medicines. Background technique [0002] At present, there are many products on the market for removing acne and acne marks on the face, but the effect is relatively single and limited, or it is inconvenient to use, especially for some people with wrinkled, freckled, and acne-prone faces, but they cannot be completely effective and perfect. the goal of. [0003] In recent years, it has been found that both chitin and chitosan and their derivatives are widely used in medicine, agriculture, food and non-food industries. It is considered to be a new type of physiological material with superb functions, all of which Uses stem from their diverse biological functions, especially biocompatibility and complete degradability and extremely low toxicity of metabolites during degradation [1] . Studies have ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61P17/00A61P17/04A61P17/10A61P15/02A61K31/722A61K35/64A61K36/00A61K36/718A61K35/644
Inventor 黄德智赵敬国徐群朱敏徐峰黄雯徐强徐曼
Owner DALIAN POLYTECHNIC UNIVERSITY
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