Preparation method of carbon nano-tube reinforced silicon-containing hydroxylapatite bone-cement biological material

Abstract

The invention relates to a method for preparing a nanotube-reinforced silicon-substituted hydroxyapatite and bone cement biomaterial, which comprises the following steps of: mixing a solution of calcium nitrate, a solution of ammonium dibasic phosphate and a solution of urea to obtain D; adding a chemical pure tetraethyl orthosilicate solution into the solution D and placing the mixture in a microwave chemical reactor for reaction to obtain a white suspension; removing a supernatant of the suspension through filtration to obtain a sample E; drying, calcining and grinding the sample E to obtain silicon-substituted hydroxyapatite powder, adding a silane coupling agent and absolute ethanol into the silicon-substituted hydroxyapatite powder and subjecting to mixture to ultrasonic dispersion to obtain F; placing carbon fibers in deionized water, adding carboxymethylcellulose sodium, the sample F and potassium persulfate into the deionized water and subjecting the mixture to ultrasonic dispersion to obtain G; mixing acrylic acid and itaconic acid to obtain a mixed solution H1; adding sodium citrate into the mixed solution H1 to obtain a mixed solution H2; and placing a sample of K in a watch glass, adding the solution H2I into the watch glass, transferring the mixture into a mould for curing and obtaining the target product. In the composite prepared by the method, the carbon fibers distribute uniformly and are desirably combined with a substrate interface, so the composite is a biomedical composite with wide application prospect.

Description

technical field [0001] The invention relates to a preparation method of reinforced bone cement biological material, in particular to a preparation method of carbon fiber reinforced silicon-containing hydroxyapatite bone cement biological material. Background technique [0002] Hydroxyapatite is the main inorganic component of vertebrate bones and teeth, and has excellent biocompatibility and bioactivity. Human bone cells can form chemical bonds directly on hydroxyapatite, and the bonding strength is high and the stability is good, so it is widely used as a hard tissue replacement material. However, hydroxyapatite itself has low strength and high brittleness, so it can only be used in non-load-bearing materials such as alveolar ridge enhancement, ear ossicle replacement, and maxillofacial bone repair, but it is difficult to apply to load-bearing bones, so p-hydroxyapatite is needed Stone strengthens and toughens. At present, the domestic and foreign methods of strengthening...

AI Technical Summary

Problems solved by technology

Although the mechanical properties of the composite materials prepared by the above methods have been improved, the operation is complicated and the reaction conditions are not easy to control.