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Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof

The technology of Ganoderma lucidum and compound prescription is applied in the field of traditional Chinese medicine compound Ganoderma lucidum preparation and its preparation, which can solve the problems of many impurities, no tumor inhibition test and immunity improvement test, undisclosed drug efficacy and toxicology research results, etc. Tumor inhibition rate, good anti-cancer clinical effect, strong production process operability effect

Active Publication Date: 2011-06-29
北京九九方元保健品经销有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent 93100151.X discloses compound Ganoderma lucidum oral liquid and its preparation method. The prescription is composed of Ganoderma lucidum, Acanthopanax, Shouwu, Wudou, etc. There is no detailed tumor inhibition test and immunity improvement test, which is consistent with the present invention different prescription
In the above technologies, the method of directly crushing medicinal materials into medicine is mostly adopted, and the method of extraction and inclusion of volatile oil into medicine is rarely used. There are many impurities in the prescription, and the absorption and utilization of human body has certain limitations.
In addition, the anti-cancer Ganoderma lucidum compound preparations in the above documents or patents have not disclosed the drug efficacy and toxicological research results of the system

Method used

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  • Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof
  • Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof
  • Anti-cancer traditional Chinese medicine compound ganoderma preparation and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0018] Chinese medicine compound Ganoderma lucidum granule of the present invention is prepared by described weight by following raw material:

[0019] Ganoderma lucidum 150kg, Ganoderma lucidum spore powder 40kg, Atractylodes macrocephala 30kg, Panax notoginseng 10kg, Chuanxiong 10kg, Silkworm 7kg, Hedyotis diffusa 7kg, Smilax 7kg, Licorice 4kg.

[0020] The preparation process of its granules is as follows:

[0021] Take Atractylodes macrocephala according to the above weight, steam distill for 1.5-2.5 hours, distill the obtained volatile oil, add 5-10 times the amount of β-cyclodextrin, add an appropriate amount of water, add it to a colloid mill, grind for 30 minutes, and vacuum dry at a temperature lower than 40°C to obtain Atractylodes volatile oil inclusion compound: according to the above weight ratio, take Ganoderma lucidum, Chuanxiong, Hedyotis diffusa, Smilax cocos, Bombyx mori, and the residue of the above-mentioned distilled Atractylodes volatile oil, add 8-10 tim...

Embodiment 2

[0023] Chinese medicine compound Ganoderma lucidum granules of the present invention are prepared by the following raw materials according to the weight ratio:

[0024] Ganoderma lucidum 4000g, Ganoderma lucidum spore powder 600g, Atractylodes macrocephala 400g, Panax notoginseng 200g, Ligusticum chuanxiong 200g, Silkworm 150g, Hedyotis diffusa 150g, Smilax 150g, Licorice 60g.

[0025] Its granules are prepared according to the preparation method of Example 1.

Embodiment 3

[0027] Chinese medicine compound Ganoderma lucidum granules of the present invention are prepared by the following raw materials according to the weight ratio:

[0028] Ganoderma lucidum 2100g, Ganoderma lucidum spore powder 430g, Atractylodes macrocephala 290g, Panax notoginseng 145g, Ligusticum chuanxiong 130g, silkworm 87g, Hedyotis diffusa 87g, Smilax 87g, licorice 50g.

[0029] Its granules are prepared according to the preparation method of Example 1.

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Abstract

The invention discloses an oral traditional Chinese medicine compound Mythic Fungus preparation and preparation method thereof, which belongs to the medicine and health product technology field. The preparation is made from the following raw materials according to the weight parts of: Mythic Fungus 1500-4000 parts, Mythic Fungus spore powder 400-600 parts, bighead atractylodes rhizome 250-400 parts, pseudo-ginseng 100-200 parts, Ligusticum wallichii 100-200 parts, muscardine silkworm 70-150 parts, heydyotis 70-150 parts, Smilax glabra 70-150 parts and licorice 40-60 parts. The medicament in the invention has stable anticancer effective components, has a high tumor inhibitory ratio verified by various in vivo / vitro tests, can increase body immunity substantially, has definite antitumor effect, and can be combined with chemotherapeutics to improve the effect while reduce the toxicities of the chemotherapeutics.

Description

technical field [0001] The invention relates to an orally administered traditional Chinese medicine compound ganoderma preparation and a preparation method thereof. The traditional Chinese medicine compound ganoderma preparation of the invention uses ganoderma lucidum medicinal material and its spore powder as main raw materials, is prepared through extraction, refinement and granulation, and is mainly used for preventing and treating cancer and improving body immunity, and belongs to the technical field of medicine and health care products. Background technique [0002] Ganoderma lucidum is a treasure in the treasure house of traditional Chinese medicine, and it is an extremely important medicinal material in traditional Chinese medicine. A large number of pharmacology and clinical practice have proved that Ganoderma lucidum medicinal materials and spore powder have strong anti-tumor effects. Triterpene acid has a strong inhibitory effect on a variety of cancer tumor cells,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/16A61P35/00A61K35/64
Inventor 董英杰艾莉穆瑛俊韩亚男
Owner 北京九九方元保健品经销有限公司
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