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Medicament composition for curing vulva inflammation and vulvar pruritus and method of preparing the same

A composition and technology for vulvitis, applied in the field of new drugs, can solve the problems of easy repeated infection, lingering disease course and difficult to heal, affecting the quality of life of women, etc., and achieve the effects of stable quality, exact curative effect and simple production process

Inactive Publication Date: 2008-10-08
BEIJING ZHONGKE RENHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Vulvitis and genital itching will bring unspeakable suffering to women, and it is very easy to re-infect, and the course of the disease is mostly lingering and difficult to heal, which seriously affects the quality of life of women

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Prescription composition:

[0027] Sophora flavescens 40g Cnidium 30g Phellodendron 20g

[0028] Artemisia argyi 15g Scutellaria baicalensis 20g Dandelion 20g

[0029] White fresh skin 15g Chinese prickly ash 10g

[0030] Benzoic acid 5g

[0031] Make a total of 1000ml

[0032] (1) Take Sophora flavescens, pulverize into coarse powder, extract with 10 times the amount of 60% ethanol under reflux for 2 hours, extract the alcohol solution and filter; add 8 times the amount of 60% ethanol to reflux extract for 2 hours, extract the alcohol solution and filter; Add 8 times the amount of dregs of 60% ethanol to reflux and extract for 1 hour, extract the alcohol solution and filter; combine the filtrates, recover ethanol under reduced pressure and concentrate it to a clear paste with a relative density of 1.15 (60°C) for later use; volatilize the ethanol from the dregs ,spare;

[0033] (2) Get Fructus Cnidii, use 8 times the amount of 85% ethanol to reflux extract for 2 h...

Embodiment 2

[0039] Prescription composition:

[0040] Sophora flavescens 40g Cnidium 30g Phellodendron 20g

[0041] Artemisia argyi 15g Scutellaria baicalensis 20g Dandelion 20g

[0042] White fresh skin 15g Chinese prickly ash 10g glycerin 10g

[0043] Polysorbate 80 2g

[0044] Make a total of 1000ml

[0045] Preparation:

[0046] (1) Take Sophora flavescens, crush it into a coarse powder, use 10 times the amount of 75% ethanol to reflux extract for 2 hours, extract the alcohol solution and filter; add 10 times the amount of 75% ethanol to reflux extract for 2 hours, extract the alcohol solution and filter; Add 10 times the amount of 75% ethanol to the dregs and extract under reflux for 1 hour, and filter the alcohol solution; combine the filtrates, recover ethanol under reduced pressure and concentrate to a clear paste with a relative density of 1.25 (55°C) for later use; dregs evaporate ethanol ,spare;

[0047] (2) Get Fructus Cnidii, use 10 times the amount of 85% ethanol to re...

Embodiment 3

[0053] Prescription composition:

[0054] Sophora flavescens 40g Cnidium 30g Phellodendron 20g

[0055] Artemisia argyi 15g Scutellaria baicalensis 20g Dandelion 20g

[0056] White fresh skin 15g Chinese prickly ash 10g citric acid 88g

[0057] PEG6000 45g Sodium bicarbonate 130g

[0058] A total of 1000 pieces were made

[0059] Preparation:

[0060] (1) Take Sophora flavescens, crush it into a coarse powder, use 10 times the amount of 75% ethanol to reflux extract for 2 hours, extract the alcohol solution and filter; add 10 times the amount of 75% ethanol to reflux extract for 2 hours, extract the alcohol solution and filter; Add 10 times the amount of 75% ethanol to the dregs and extract under reflux for 1 hour, and filter the alcohol solution; combine the filtrates, recover ethanol under reduced pressure and concentrate it to a clear paste with a relative density of 1.15 (55°C) for later use; volatilize the ethanol from the dregs ,spare;

[0061](2) Get Fructus Cnidi...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating vulvitis and vulvae itching and a preparation method thereof. The pharmaceutical composition has the functions of removing heat, detoxification, demoistening, killing bacterium, relieving itching and removing dirty matters and is used for treating the diseases of itching, redness and swelling and pain in vulvae caused by vulvitis or vaginitis. The pharmaceutical composition adopts the modern preparation technology and can be processed to any formulation of external lotion, embrocation or effervescent tablet for gynaecology treatment which is applicable to the clinical wide application. The pharmaceutical composition is characterized by simple production technique, stable quality, convenient use, safety and no side effect, etc., thus having good efficacy.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating vulvitis and vulvar itching and a preparation method thereof, belonging to the technical field of new drugs. Background technique [0002] Inflammation of the vulva is the most common disease in gynecology. The clinical manifestations are itching, pain or burning sensation of the vulva, and swelling of the vulva. [0003] There are many pathogenic factors of vulvar inflammation, and the most common clinical cause is pathogenic bacteria infection, with Enterobacteriaceae, Candida albicans and Trichomonas being the most common, vaginitis, unclean vulva, vulvar eczema, vulvar dermatitis Diabetes, diabetes and other diseases can cause inflammatory diseases of the vulva. At the same time, high mental stress, fatigue, mental trauma or conditioned reflexes can also cause inflammatory diseases of the vulva. [0004...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P15/02A61P17/00
Inventor 颜丽君
Owner BEIJING ZHONGKE RENHE SCI & TECH
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