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Compound dragon's blood gel preparations and extraction and preparation technique

A technology of gel preparation and dried blood, which is applied in the field of compound dried blood gel preparation and its extraction and preparation technology, can solve the problems of poor appearance of the gel, high content of impurities in the extract, and large loss of active ingredients, so as not to pollute the clothes , Guarantee the quality and its uniformity, and the effect of quality control

Inactive Publication Date: 2008-09-17
湖北中医学院
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AI Technical Summary

Problems solved by technology

The extraction process of the original compound blood jellyfish gel is the traditional ethanol percolation method, which has the disadvantages of large loss of active ingredients, more impurities in the extracted extract, and poor appearance of the prepared gel.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: The traditional Chinese medicine compound Xuejie gel preparation prepared by the present invention, wherein the medicinal component frankincense is to extract the volatile oil according to the above-mentioned steam distillation method, and Corydalis and Angelica are obtained by using the above-mentioned supercritical CO 2 Extraction technology, extracting and separating the effective parts respectively, collecting the extract, and preparing it into a gel together with dried blood and borneol.

[0035] Its extraction process is:

[0036] 1) Crush the Rhizoma Corydalis into 20-60 meshes, weigh 100 grams, mix well with concentrated ammonia water-70% ethanol (the volume ratio of concentrated ammonia water and 70% ethanol is 1:20), seal it for 24 hours, pack into a 1-liter extraction tank, when the pressure of the separation tank I and the separation tank II reached 5MPa and the temperature reached 50°C, continuously pump 200 milliliters of 95% ethanol, CO 2 T...

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Abstract

The invention relates to a gel preparation of compound dragon's blood and an extraction preparation technology. The preparation is made of the active pharmaceutical ingredient of the gel powder and the gel substrate of original compound dragon's blood. The extraction adopts the super-critical extraction technology with CO less than SUB and SUB more than 2 and 2 less than and the vapor distillation to extract and separate the effective part of the prescription pharmaceutical ingredient, and macromolecule Carbomer-940, propanediol, triethanolamine and distilled water are chosen to prepare the gel substrate. The invention has the advantages of better biological adhesiveness, good skin permeability, everlasting function, reducing the toxicity and adverse reaction of the medicine, small consumption, rapidly taking effect, convenient use, comfortable feel, convenient washing, no pollution of clothes and stable quality.

Description

technical field [0001] The invention relates to an externally-used traditional Chinese medicine compound blood jellyfish gel preparation and its extraction and preparation process. Compound blood jelly gel prescription medicinal materials, respectively using supercritical CO 2 The effective parts are extracted and separated by extraction technology and steam distillation method, and the original ethanol percolation extraction process is replaced. The polymer gel is used as the matrix to prepare a gel preparation for the treatment of soft tissue injuries. Background technique [0002] Compound Xuejie Gel is an effective prescription that has been clinically used for more than 20 years. The prescription is composed of five flavors of traditional Chinese medicine, Corydalis Corydalis, Xuejie, Frankincense, Angelica, and Borneol. damage. [0003] The medical treatment of acute soft tissue injuries in China is mainly based on traditional Chinese medicine and its compound extern...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/00A61K47/32A61P29/00A61P19/04A61K31/045
Inventor 刘超英鲁汉兰韩建伟刘丹
Owner 湖北中医学院
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