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Medicine for treating rheumatoid and atrophic arthritis

A rheumatoid and rheumatoid technology, applied in the direction of drug combination, drug delivery, antipyretics, etc., can solve the problems of short maintenance time, poor patient acceptance, large dosage, etc., and achieve reduced volume, convenient transportation and use Effect

Active Publication Date: 2008-07-30
成都芝芝药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, Baoguang Rheumatism Liquid with Qianghuo, Duhuo, Chuanxiong, safflower, antler glue, turtle shell glue, etc. as the main medicinal ingredients is inconvenient to use, has a large loss of liquid medicine, less absorption by the body, and has no obvious effect; chicken blood Tengfengding Capsules, such as Teng, Jiujiefeng, Baitongcao, Zanthoxylum bungeanum, etc., are effective medicinal ingredients. Due to their large dosage, high cost, serious adverse reactions, and low patient acceptance; The Gucixiaotong Capsules with Baizhi, Fenmu, Chuanshanlong, Yiyiren, Tiannanxing, etc. as the main drug ingredients, the prescription structure is not reasonable, so the effective time is slow, the analgesic effect is poor, and the maintenance time is short
In terms of chemical drugs, mainly non-steroidal anti-inflammatory drugs, serious gastrointestinal side effects, poor acceptance by patients
Among the currently used Chinese patent medicine preparations, the traditional dosage form of the preparation is directly crushed with medicinal raw materials, the absorption of effective medicinal ingredients is small, it is difficult to fully exert its effect, the waste of medicinal raw materials is large, and the volume of the medicine is large, making it difficult for patients to take it. Poor acceptance, transportation, storage, etc. are also inconvenient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Ingredients: coix seed 300g, chuanxiong 150g, atractylodes 175g, angelica 100g

[0022] Codonopsis 170g Asarum 20g Astragalus 200g Clematis 50g

[0023] Preparation:

[0024] Properly pulverize the coix seed in the above raw materials, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time is 4 hours, and the second time is 2 hours, recover the ethanol, dry, and pulverize to obtain the coix seed extract powder; Add 6 times the amount of water to soak Qiwei raw materials other than kernels for 1 hour, extract the volatile oil by distillation for 3 hours, collect the volatile oil, filter, and collect the distilled aqueous solution in another device; After 1.5 hours, filter, combine the filtrate with the above aqueous solution, concentrate to a clear paste with a relative density of 1.10 (60-70°C), add ethanol to make the alcohol content reach 70%, stir well, let stand for 24 hours, filter, and filtrate Recover ethanol, concentrate to...

Embodiment 2

[0026] Ingredients: coix seed 225g, chuanxiong 225g, atractylodes 150g, angelica 150g

[0027] Codonopsis 150g Asarum 37.5g Astragalus 150g Clematis 75g

[0028] Preparation:

[0029]Properly pulverize coix seed, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time is 4 hours, the second time is 2 hours, recover ethanol, dry, and pulverize to get coix seed extract powder; Add 6 times the amount of water to soak for 1 hour, extract the volatile oil by distillation for 3 hours, collect the volatile oil, filter, and collect the distilled aqueous solution in another device; add 10 times the amount of water to decoct the medicinal residue twice, 1.5 hours each time, filter, Combine the filtrate with the above aqueous solution, concentrate to a clear paste with a relative density of 1.10 (60-70°C), add ethanol to make the alcohol content reach 70%, stir well, let stand for 24 hours, filter, recover ethanol from the filtrate, and concentrate to...

Embodiment 3

[0031] Ingredients: coix seed 150g, chuanxiong 300g, atractylodes 200g, angelica 120g

[0032] Codonopsis 100g Asarum 55g Astragalus 140g Clematis 100g

[0033] Preparation:

[0034] Properly pulverize coix seed, add 8 times the amount of water to extract twice, each time for 2 hours, concentrate to a thick paste with a relative density of 1.25-1.30 (70-80°C), dry, and pulverize to obtain coix seed extract powder; Add 6 times the amount of water to soak the Qiwei medicines other than kernels for 1 hour, extract the volatile oil by distillation for 3 hours, collect the volatile oil, filter, and collect the distilled aqueous solution in another device; add 10 times the amount of water to decoct the medicinal residue twice, 1.5 hour, filter, the filtrate is combined with the above aqueous solution, concentrated to a clear paste with a relative density of 1.10 (60-70°C), add ethanol to make the alcohol content reach 70%, stir well, let stand for 24 hours, filter, and re...

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PUM

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Abstract

The invention relates to a medicine used for treating rheumatoid arthritis and proliferative arthritis, which takes extraction of medicinal raw materials such as Jobstears Seed, RhizomaChuanxiong, atractylodes, angelica, codonopsis pilosula, asarum, radix astragali and radix clematidis as effective ingredients which is jointly constituted with acceptable auxiliary ingredients in pharmacy. The medicine of the invention adopts the natural medicinal raw materials as the effective ingredients, has the advantages of simple preparation method, precise healing effect and safe taking, etc., and is easily popularized and applied.

Description

technical field [0001] The invention relates to a medicine for treating rheumatic and rheumatoid arthritis, which uses natural medicinal raw materials as effective medicine components. Background technique [0002] Rheumatoid and rheumatoid arthritis is a systemic chronic disease mainly characterized by non-infectious inflammation of joints and periarticular tissues. It is called Bi disease in traditional Chinese medicine and is one of the common clinical diseases and refractory diseases. The main symptoms may include soreness, pain, and swelling in limbs and joints, which may aggravate with changes in the external weather. In severe cases, it may cause joint contractures, difficulty in flexion and extension, and even enter the viscera from the meridians, causing qi and blood obstruction in the viscera. Closed certificate. Its etiology is mostly caused by wind-cold-damp evil attacking the human body, and the clinical syndromes are different depending on the degree of its in...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P29/00A61P19/02
Inventor 王建生
Owner 成都芝芝药业有限公司
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