System for preparing micro particles with hydraulic cavitation reinforcing supercritical auxiliary atomizing and its method

Abstract

The invention discloses a system of waterpower cavitation enhanced supercritical assistant pulverization preparing particle and a method thereof, which has the following character that: (1) sieve plate is mounted in the waterpower cavitation mixer to form cavity, inanition and cavum in the miscible liquid flow of supercritical CO2 and solution to realize the rapid mixture thereof, and to make the meltage of the supercritical CO2 in the solution approach the equilibrium solubility; (2) the mixture of the supercritical CO2 and solution is sprinkled into the precipitator by nozzle to form secondary liquid drop, which is heat transfer and mass transfer with N2 to make the liquid vaporize, and then get particle; (3) the particle is collected using the sintered plate mounted on the bottom of the precipitator; (4) the mixing gas of CO2, N2 and solvent enter into the condenser, and the solvent is reclaimed and recycling. The operating condition of the invention is relative mildness, the operating process is simple, the residual of the solvent is low, and the size distribution of the product is narrow. The invention can be used for grain diminution of various of material.

Description

technical field [0001] The invention relates to a system and a method for preparing microparticles by hydraulic cavitation enhanced supercritical atomization. Background technique [0002] At present, the methods of particle preparation mainly include mechanical pulverization, liquid anti-solvent method, spray drying method and freezing method. Although these methods are simple to operate, there are some shortcomings and deficiencies, such as large amount of organic solvent, high content of residual organic solvent in the product, serious heat-sensitive degradation of the solute to be micronized, etc. The most important thing is that these methods are difficult to control the product. particle size, distribution and product morphology. Although these methods still play an important role in the production of bulk petrochemical products, in recent years, with the increasing demand for food and medicine (variety, quality), these traditional methods have become increasingly dif...

AI Technical Summary

Problems solved by technology

Although the SAA technology has been improved compared with the original CAN-BD process, there are still problems such as the slow mass transfer rate of supercritical carbon dioxide and solution between the two phases in the saturator, resulting in low mixing efficiency and long residence time. It is easy to cause early precipitation of solutes and affect product quality

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