Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine soft capsule and its preparing process and quality controlling means

A technology of soft capsules and traditional Chinese medicines, which is applied in capsule delivery, pharmaceutical formulations, antibacterial drugs, etc., and can solve the problems of undiscovered nude flowers and purple pearls

Inactive Publication Date: 2007-08-15
杨文龙
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After reviewing the existing literature, no literature has been found to make soft capsules from Nadihuazizhu, so it is necessary to conduct research on the preparation method and stability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine soft capsule and its preparing process and quality controlling means
  • Traditional Chinese medicine soft capsule and its preparing process and quality controlling means

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] prescription:

[0064] Cystic fluid: 10kg of dried extract powder of Auranthus japonica, 12kg of soybean oil, 0.4kg of beeswax

[0065] Capsule shell: gelatin 110kg, glycerin 50kg, water 100kg, ethylparaben 15kg, iron oxide red 2.0kg;

[0066] Preparation:

[0067] ①Preparation of dry extract powder of Zizhu nudiflora

[0068] Add water to decoct the naked flower purple pearl twice, the first time for 2 hours, the second time for 1.5, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a clear paste (60°C) with a relative density of 1.10, dry, dry The extract powder is passed through a 120-mesh sieve to obtain the dry extract powder of Auranthus nudiflora;

[0069] ② Preparation of cystic fluid

[0070] Add soybean oil as a dispersant and beeswax as a suspending agent to the dry extract powder of Zizhu nudiflora, and grind until uniformly mixed in a colloid mill;

[0071] ③Preparation of capsule shell

[0072] Put the gelatin in w...

Embodiment 2

[0075] prescription:

[0076] Cystic fluid: 12kg of dried extract powder of Aurora nudiflora, 16kg of peanut oil, 0.7kg of lecithin, 0.1kg of Tween-80

[0077] Capsule shell: gelatin 100kg, glycerin 30kg, water 120kg, ethylparaben 8kg, iron oxide black 3.0kg;

[0078] Preparation:

[0079] ①Preparation of dry extract powder of Zizhu nudiflora

[0080] Add water and decoct 3 times, the first time is 3 hours, the second time is 1.5 hours, the third time is 1 hour, the decoction is combined, filtered, and the filtrate is concentrated under reduced pressure to a clear paste with a relative density of 1.05 ( 60 DEG C), dry, and the dry extract powder passes through a 120-mesh sieve to obtain the naked flower purple pearl dry extract powder;

[0081] ② Preparation of cystic fluid

[0082] Add peanut oil as a dispersant, lecithin as a suspending agent and Tween-80 as a surfactant to the dry extract powder of Auranthus nudica, and grind until uniformly mixed in a colloid mill;

...

Embodiment 3

[0087] prescription:

[0088] Cystic fluid: 15kg of dried extract powder of Auranthus japonica, 14kg of sesame oil, 0.6kg of ethyl cellulose, 0.1kg of glycerol monostearate, 600.1kg of Span-600.1kg;

[0089] Capsule shell: gelatin 80kg, glycerin 60kg, water 110kg, ethylparaben 16kg, iron oxide red 0.5kg;

[0090] Preparation:

[0091] ①Preparation of dry extract powder of Zizhu nudiflora

[0092] Add water to decoct the naked flower purple pearl twice, the first time for 1 hour, and the second time for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a clear paste (60°C) with a relative density of 1.15, dry, dry The extract powder is passed through a 120-mesh sieve to obtain the dry extract powder of Auranthus nudiflora;

[0093] ② Preparation of cystic fluid

[0094] Add dispersant sesame oil, suspending agent ethyl cellulose, antiseptic glycerin monostearate, surfactant Span-60 to the dry extract powder of Nadihua Zizhu, and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicinal soft capsule for treating inflammation caused by bacterial infection, acute infectious hepatitis, and hemorrhage of respiratory tract and digestive tract, and its preparation quality control and method. The preparation method comprises adding disperser and suspending agent to dry extract powder of Nakedflower beautyberry, colloid milling, and making to soft capsule through pressing or dripping method. The soft capsule has the advantages of simple preparation, good stability, low cost, high bioavailability, good taste, and convenient administration; and can be used for treating inflammation caused by bacterial infection, acute infectious hepatitis, and hemorrhage of respiratory tract and digestive tract.

Description

technical field [0001] The invention discloses a traditional Chinese medicine soft capsule, in particular relates to a traditional Chinese medicine soft capsule for treating inflammation caused by bacterial infection, acute infectious hepatitis, respiratory tract and digestive tract bleeding, and at the same time, the invention also discloses the traditional Chinese medicine soft capsule methods of preparation and quality control. Background technique [0002] Verbenaceae Purple Pearl is a precious heritage of my country's medical treasure house. According to the existing records in my country, there are about 46 species of plants in the genus Gallicarpa nudiflora Hook. et Arn. Among them, Gallicarpa nudiflora Hook. et Arn. has been used as medicine and treatment of diseases since ancient times, and has a wide range of applications. In the 1970s, the drug began to be paid attention to by people. It has good effects in hemostasis, treatment of burns, treatment of hemorrhoids...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/85A61K9/48A61K47/42A61P31/04A61P11/00A61P1/12A61P1/00A61P7/04G01N21/31G01N31/22
Inventor 杨文龙
Owner 杨文龙
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com