The invention relates to an immunohistochemical detection kit for human CD26 and its clinical application, belonging to the field of
in vitro diagnosis. The immunohistochemical detection kit disclosed in the present invention adopts a brand-new anti-human CD26
antibody, and its
heavy chain variable region contains the following complementarity determining regions: the
amino acid sequences are as shown in SEQ ID NO: 1, 2, 3 respectively HCDR1, HCDR2, HCDR3; and their light chain variable region sequences contain the following complementarity determining regions: LCDR1, LCDR2, LCDR3 shown in SEQ ID NO: 4, 5, 6, respectively. The specificity of the anti-human CD26
antibody used in the present invention can meet the performance requirements of the immunohistochemical kit, and it can be a mouse
antibody or a recombinantly expressed chimeric human antibody, which is convenient for
mass production, wherein the recombinantly expressed
chimeric antibody Combined with human antibodies to reduce human anti-mouse antibody reactions and non-
specific adsorption, it can also meet the needs of large-scale clinical applications. When using the CD26
target drug, the immunohistochemical kit of the present invention can be used together to achieve the effect of precise treatment.