Sunscreen Compositions
a technology of compositions and sunscreens, applied in the field of sunscreen compositions, can solve the problems of affecting the appearance of sunburn from an overexposure, affecting the health of patients, and affecting the effect of sunburn, so as to achieve a more natural appearance on the skin, blur fine lines and blemishes, and diffuse transmittance high
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example 1
[0051]Compositions 1-22 were prepared according to base formula of Table 1. The nylon, silica, and barium sulfate were either absent or present in the indicated amount depending on the sample, as shown in Tables 2-4. The Nylon particles were porous nylon-6 particles treated with hydrogen dimethicone (POMP 605-S101 from UBE Industries). The silica particles were spherical silica available from Kobo Products as MSS-500W. Barium sulfate particles were either “USP Barium Sulfate for Formulation” from Mallinckrodt Inc or “Blanc Fixe XR-HN” from Sachtleben Chemie GmbH.
[0052]Tables 2-4 indicate the presence (+) or absence (−) of an organic sunscreen, barium sulfate, nylon, silica, or iron oxide in each composition. When present, the amount of barium sulfate was 5 wt %, the amount of nylon was 5 wt %, the amount of silica was 2.5 wt %, and the amount of OMC was 7.5 wt %, and the amounts of homosalate and octyl salicylate were each 5 wt %. For compositions where a component was omitted, cast...
example 2
[0058]Samples #11-14 were prepared to assess the role of each of the three components (barium sulfate, nylon, and silica) in enhancing SPF of an organic sunscreen. Sample #11 contained 7.5% OMC, 0.50% silica-coated iron oxide, 5% nylon and 2.5% silica, without barium sulfate. Sample #12 contained 7.5% OMC, 0.50% silica-coated iron oxide, and 5% nylon, without silica and barium sulfate. Sample #13 contained 7.5% OMC, 0.50% silica-coated iron oxide, and 2.5% silica, without nylon and barium sulfate. Sample #14 contained 7.5% OMC, 0.50% silica-coated iron oxide, and 5% barium sulfate, without nylon and silica. Samples #11-14 were evaluated for SPF and diffuse transmittance according to the procedure above. The data is summarized below, along with sample #9 (containing all three components) for comparison.
TABLE 37911121314OMC++++++Nylon−+++−−Silica−++−+−Barium Sulfate−+−−−+Iron Oxide,++++++silica-coatedSPF18.9435.6923.0222.2622.3024.25Diffuse38.6950.5549.2746.7135.7547.93Transmittance
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example 3
[0060]Samples #15-22 were prepared to study the effect of the three-component system with other organic sunscreens, namely, homosalate and octyl salicylate.
TABLE 41516171819202122OMC++−−++−−Homosalate++++−−−−Octyl−−−−++++salicylateNylon+−+−+−+−Silica+−+−+−+−Barium Sulfate+−+−+−+−Iron Oxide,++++++++silica-coatedSPF28.3322.6312.217.7224.6321.4012.659.44Diffuse52.9340.0354.8338.2354.1340.0755.2639.16Transmittance
[0061]Octyl salicylate (5%) or homosalate (5%), were added with or without OMC to the samples with or without nylon, silica, and barium sulfate. Comparing sample #15 to #16, #17 to #18, #19 to #20, and #21 to #22, the in vitro SPF is higher in all samples containing nylon, silica, and barium sulfate vs. their respective controls without the three components, indicating that the combination boosts SPF of other organic sunscreens.
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