Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Non-fermented compositions comprising a cereal based fraction and a probiotic and uses thereof

a technology of probiotics and compositions, applied in the field of nonfermented compositions, can solve problems such as obstructing the proliferation of pathogenic bacteria, and achieve the effect of increasing the barrier function of the gut mucosa

Inactive Publication Date: 2012-11-29
PROBI AB LUND SE
View PDF7 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention is about a non-fermented composition that can increase the production of butyric acid in the colon. It contains a mix of cereal-based ingredients and a specific type of probiotic bacteria called Lactobacillus. This composition can be used as a synbiotic (a combination of probiotics and prebiotics) to treat metabolic syndrome, ulcerative colitis, Crohn's disease, IBS, and IBD. It can also help maintain a healthy gut and provide better protection against harmful bacteria.

Problems solved by technology

High amounts of probiotic bacteria may obstruct the proliferation of pathogenic bacteria.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Non-fermented compositions comprising a cereal based fraction and a probiotic and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016]The present invention relates to a non-fermented composition having the ability to increase the formation of butyric acid in the colon and comprising at least one cereal based fraction and at least one isolated probiotic strain of Lactobacillus. The meaning of the phrase “having the ability to increase the formation of butyric acid in the colon” means that the present non-fermented composition comprising both a probiotic and a cereal based fraction will increase the formation of butyric acid in the colon and in blood, see table 4 and 5, compared to when a cereal based fraction is given only without a probiotic. In table 4 the formation of butyric acid in the colon has increased 157% (from 7 to 18 μmol / g) for whole grain barley, 50% (from 12 to 18 μmol / g) for malted barley and 33% (from 9 to 12 μmol / g) for Brewers spent grain. Thus, an increase of the formation of butyric acid is in the range of 30-200%, preferably in the range of 40-180%, more preferably in the range of 50-160...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
sizeaaaaaaaaaa
particle sizeaaaaaaaaaa
dry weightaaaaaaaaaa
Login to View More

Abstract

The present invention relates to a non-fermented composition having the ability to increase the formation of butyric acid in the colon and comprising at least one cereal based fraction and at least one isolated probiotic strain of Lactobacillus as well as the use of said non-fermented composition as a synbiotic and for treatment of the metabolic syndrome, ulcerative colitis, Crohns disease, Irritable bowel syndrome (IBS), or Inflammatory bowel disease (IBD). The non-fermented composition of the invention is useful for the maintenance of a healthy gut-mucosa and / or for the provision of an increased barrier function of the gutmucosa.

Description

TECHNICAL FIELD OF THE INVENTION[0001]The present invention relates to a non-fermented composition having the ability to increase the formation of butyric acid in the colon, as well as to different uses of said non-fermented composition such as for the maintenance of a healthy gut-mucosa by the provision of an increased barrier function.BACKGROUND ART[0002]Butyric acid and glutamine have been proposed to be important for colonic health. Pure barley β-glucans have been shown to give comparatively high amounts of butyric acid, and germinated barley foodstuff, obtained from brewer's spent grain (BSG), containing high amounts of β-glucans and glutamine, has been reported to reduce the inflammatory response in the colon of subjects with ulcerative colitis.[0003]There has been much recent interest in the relationship between dietary fiber, health-promoting bacteria and the prevention of inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis.[0004]Dietary fiber i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61K35/74A61P29/00A61P1/00A61P3/00A61P1/04A23L7/10A23L7/104A23L7/20
CPCA23L1/1016A23L1/105A23L1/164A23L1/185A23L1/3014A23V2002/00A61K36/899A61K35/74A23Y2220/67A23V2200/3204A23V2200/3202A23L7/115A23L7/104A23L7/117A23L7/20A23L33/135A61P1/00A61P1/04A61P29/00A61P3/00A61P3/04A23V2400/169A23L33/10A61J3/02A61J3/07A61K39/07A61K36/8998A61K35/747A23V2400/175A61K2035/115A23V2200/32
Inventor BRANNING, CAMILLANYMAN, MARGARETA
Owner PROBI AB LUND SE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com