Production of benzyl lidocaine halogenated amine
A benzyl lidocaine ammonium halide, production method technology, applied in chemical instruments and methods, preparation of organic compounds, organic chemistry and other directions, can solve problems such as high production cost, large solvent consumption, etc., achieve short reaction time, solvent Low dosage effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0015] Add 400Kg lidocaine and 240Kg benzyl chloride into a 1000L reaction kettle, then add 300Kg cyclohexane, heat and reflux for 12 hours under stirring, then cool to room temperature, filter, wash the solid with an appropriate amount of cyclohexane, and dry to obtain 530Kg Benzyl lidocaine ammonium chloride, yield 86.0%, content 99.3%. The resulting mother liquor and washings were combined by filtration.
Embodiment 2
[0017] 400Kg lidocaine and 240Kg benzyl chloride are added in the 1000L reactor, then add the mother liquor and the lotion that merge among the embodiment 1, other operating conditions are with embodiment 1, obtain 561Kg benzyl lidocaine ammonium chloride, yield 91.0%, content 99.4%.
Embodiment 3
[0019] Add 400Kg lidocaine and 250Kg benzyl chloride into a 1000L reaction kettle, then add 300Kg chlorobenzene, heat and reflux for 4 hours under stirring, then cool to room temperature, filter, wash the solid with an appropriate amount of chlorobenzene, and dry to obtain 521Kg benzyl chloride. Lidocaine ammonium chloride, yield 84.5%, content 99.5%. The resulting mother liquor and washings were combined by filtration.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com