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Medicinal composition for eliminating infection and reduplication of influenza-virus

A pharmaceutical composition and influenza technology, which is applied in the field of prevention and treatment of influenza, and can solve problems such as no significant breakthroughs have been seen

Inactive Publication Date: 2006-11-15
阙壮群
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, although vaccine prevention is effective, it is not fully applicable; and in terms of antiviral agents, no significant breakthrough has been seen so far

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Experimental Materials

[0047] drug

[0048] 1. A mixture of C-phycocyanin, isophycocyanin and cyanobacteria extracted at low temperature;

[0049] 2. The anesthetic drug Ketamine;

[0050] 3. Type A influenza virus (Influenza WSN virus, three concentrations of 1500pfu, 150pfu, 15pfu.

[0051] mouse

[0052] The parental ICR mice were introduced from the National Center for Experimental Animals, and the female mice were bred to four weeks old. Each cage was fed with 8 mice as a group. The room temperature was controlled at 16-18°C, and the light cycle time was 12 hours.

[0053] The pharmaceutical composition of the invention can inhibit the replication of type A influenza virus in mice.

[0054] Experimental procedure

[0055] When the mice (female ICR mice) were raised to five weeks old, they were divided into seven groups for subsequent experiments, which were:

[0056] Group I: Force-feeding 1500 pfu of type A influenza virus and the pharmaceutical compositio...

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PUM

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Abstract

A medical composition for suppressing the infection and replication of influenza virus contains C-phycocyanin (C-CP), allophycocyanin (APC), spirulina growth factor (SGF), or their mixture. It is prepared through adding organic blue algae powder to low-tension buffer liquid, stirring, laying aside for 12 hr, separating, purifying taking upper-layer liquid, measuring optical spectrum for determining the contents of active components, and spray drying.

Description

technical field [0001] The invention relates to a pharmaceutical composition for inhibiting influenza virus infection and replication, which can be applied to the prevention and treatment of influenza. Background technique [0002] Influenza is an infectious disease caused by a viral virus, which is a virus with ribonucleic acid as its genetic material, and belongs to the family Orthomyxoviridae in virus classification. The different serum immune responses can be divided into influenza virus A, B or C (Influenza virusA, B or C). Influenza most often occurs in winter or early spring. The virus usually invades the lungs through the mouth and nose. The types of viruses vary each year. People are most susceptible to infection in crowded areas or public places. Tracing back to historical records, it can be known that this virus causes an epidemic of febrile respiratory diseases every 3-4 years. As for the worldwide pandemic, it occurs about once every 10 years. The epidemic has...

Claims

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Application Information

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IPC IPC(8): A61K38/16A23L33/195A61K9/00A61P31/16
Inventor 阙壮群施信如
Owner 阙壮群
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