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Paeonal gel and its preparing method and quality control

A technology of paeonol gel and paeonol, which is applied to the field of gel preparation and the formulation of paeonol ointment of traditional Chinese medicine formulations, can solve problems such as use limitations, and achieves reduced volatility, convenient use, and prolonged retention. effect of time

Inactive Publication Date: 2006-08-16
HEFEI LIFEON PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as a medicine for eczema, paeonol ointment is an ointment with an oil-in-water base, and its use is limited in the case of solution exudation on eczema sores during clinical application.

Method used

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  • Paeonal gel and its preparing method and quality control

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Embodiment Construction

[0060] The various formulations listed by the present invention can be implemented, so it will not be repeated here, but only an example is given for illustration.

[0061] 1. Preparation prescription

[0062] Paeonol 50g Clove Oil 7ml Tween 80 250g

[0063] Carbomer 10g Glycerin 100g Ethanol 500g

[0064] Sodium metabisulfite 1.08g Triethanolamine 8g

[0065] Distilled water balance

[0066] Make a total of 1000ml of gel

[0067] Second, the method

[0068] 1. Dissolve sodium metabisulfite in 100g of water, then add 10g of Carbomer 940 to the above solution for swelling for 12-15 hours, add glycerin and mix well for later use.

[0069] 2. Take 500ml of ethanol, add 50g of paeonol and 250g of Tween-80 until completely dissolved, then add 7ml of clove oil and mix, add this mixture to the solution obtained in (1) above, and grind for 10 minutes.

[0070] 3. Slowly add 8g of triethanolamine and grind it evenly, add water to 1000ml, and you get it.

[0071] The main drug of t...

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Abstract

A gel of paeonal as an improvement on paeonal ointment is prepared from paeonal, clove oil, tween-80, carbomer and sodium pyrosulfite. Its advantages are less volatilization of paeonal, high filming performance, slow release and high curative effect. Its preparing process and quality control method are also disclosed.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine preparation, in particular to a modified form of traditional Chinese medicine paeonol ointment-gel. Background technique [0002] Dermatitis, eczema, and urticaria are frequently-occurring diseases in skin diseases, common diseases, complex etiology, characterized by multiple rash forms, easy to ooze, protracted course of disease, and tendency to relapse. At present, the treatment of such diseases in the market is mainly based on hormone ointment, but the use of this type of medicine is easy to cause side effects, and it is not suitable for long-term use. [0003] Paeonol (Paeonol, Pae) is the main active ingredient of traditional Chinese medicine Moutan Cortex (the root bark of Paeoniasuffruticosa) and Xu Changqing (the whole herb of Cynanchum paniculatum), a traditional Chinese medicine formulation paeonol ointment, The prescription is composed of raw and auxiliary materials such as paeonol and...

Claims

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Application Information

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IPC IPC(8): A61K31/122A61K36/75A61K9/00A61P17/00
Inventor 季俊虬
Owner HEFEI LIFEON PHARMA
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