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Micro flow controlling chip DNA molecular memory

A technology of microfluidic chips and DNA molecules, applied in the field of computer science, can solve the impossible, record and store the calculation process, control and other problems

Inactive Publication Date: 2006-06-14
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

One is that the biological operations involved in the DNA calculation and the corresponding result confirmation lack a fully integrated hardware device supporting the calculation, and of course it is impossible to control the relevant parameters; the other is that all these molecular calculations are carried out only on DNA molecules. The automatic operation of the computer is not able to record and store each calculation process, and the storage function is one of the main functions of the computer in the modern sense, and it is also a basic feature of the DNA computer that is different from the DNA calculation device.

Method used

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  • Micro flow controlling chip DNA molecular memory
  • Micro flow controlling chip DNA molecular memory
  • Micro flow controlling chip DNA molecular memory

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Embodiment Construction

[0059] Depend on figure 1 It can be seen that the microfluidic chip DNA computer mainly includes a microfluidic chip workstation, a microfluidic chip, and kits for completing various molecular reactions. The microfluidic chip workstation is composed of power supply, control device and output device. It has the functions of chip energy supply and signal collection, and also manages the control of DNA computer. The DC high-voltage power supply system of the workstation is connected to eight electrodes, and different voltages can be applied to different positions of the microfluidic chip as required to control the flow of the reaction solution between the channels as required. The detector of the microfluidic chip workstation can move relative to the chip, and detect the reaction products in the algorithmic logic unit and the storage unit respectively. The chip is the core of the entire computer, and the calculation function and storage function of the computer are all complete...

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Abstract

The invention is a microflow control chip DNA molecular memory, comprising memory medium, reaction medium and microflow control chip, where the memory medium comprises known-sequence containing short-chain DNA memory cell molecules, initial operating DNA blank molecules and DNA memory molecules standing for superposed results by biochemical reaction; the microflow control chip is provided at least with memory cell region, endonuclease reaction region, enzyme-link reaction region, and result output region, where the endonuclease reaction region, enzyme-link reaction region, and result output region are interconnected through microchannel and the memory cell region is connected with the enzyme-link reaction region through microchannel. The invention adopts the microflow control chip technique to replace the widely used test tube or surface operation in the current DNA calculating course for the first time, and provides a practical possible platform for constructing a proper DNA computer by the character that the microflow control chip operates accurately and controllably and can be integrated in high flux and large scale.

Description

Technical field: [0001] The invention relates to computer science, molecular biology and microfluidic chip technology. In particular, a microfluidic chip DNA molecular computer, a microfluidic chip DNA molecular calculator, a microfluidic chip DNA molecular memory, a microfluidic chip specially used for a DNA molecular computer, and a special microfluidic chip for DNA Kit for microfluidic chips for molecular computers. Background technique: [0002] DNA computing is a new way of thinking about computing, but also about chemistry and biology. Although the biological and mathematical processes have their own complexities, they have an important commonality, that is, all the complex structures of organisms are actually obtained after some simple processing of the original information encoded in the DNA sequence, and seeking The value of a computable function with variable W can also be realized by the composition of a series of simple functions with variable W. [0003] The ...

Claims

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Application Information

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IPC IPC(8): G06N3/00G11C13/00
Inventor 林炳承李博伟解华黄振德丁永生
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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