Effervescence tablet for quickly allaying infantile fever and its preparation method

A technology for fast clearing and effervescent tablets, which is applied in the directions of antipyretics, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of poor stability, poor clarity, and difficulty in forming Chinese medicine effervescent tablets.

Active Publication Date: 2006-02-15
BEIJING INCREASE INNOVATIVE DRUG RESEARCH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problems of difficult molding, slow disintegration, poor clarity, and poor stability of traditional Chinese medicine effervescent tablets, the present invention provides an anti-effervescent tablet with a reasonable ratio of main drug and auxiliary materials, good molding, and good stability. Preparation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A kind of effervescent tablet of children's heat and speed clearing and preparation method thereof, be made of following raw material: (by grams)

[0040] Bupleurum 1250g Scutellaria baicalensis 625g Radix isatidis 1250g Pueraria 625g Honeysuckle 937.5g Buffalo horn 312.5g

[0041] Forsythia 750g Rhubarb 312.5g

[0042] Preparation:

[0043] (1) Bupleurum, honeysuckle, and forsythia add 8 times of water to distill and extract the volatile oil for 8 hours. The distilled aqueous solution is stored in another container, and the dregs are used for later use; , stirred at 50° C. for 1 hour, refrigerated overnight, filtered, dried at 40° C., and pulverized into fine powder to obtain 19.9 g of beta-cyclodextrin inclusions.

[0044] (2) Add water to the buffalo horn and decoct for 3 hours first, then decoct with distilled medicinal residues and Scutellaria baicalensis and other four flavors with water for two times, each time for 1 hour, combine the decoction, filter, and com...

Embodiment 2

[0047] A kind of effervescent tablet of children's heat and speed clearing and preparation method thereof, be made of following raw material: (by grams)

[0048] Bupleurum 1250g Scutellaria baicalensis 625g Radix isatidis 1250g Pueraria 625g Honeysuckle 937.5g Buffalo horn 312.5g

[0049] Forsythia 750g Rhubarb 312.5g

[0050] Preparation:

[0051] (1) Bupleurum, honeysuckle, and forsythia add 8 times of water to distill and extract the volatile oil for 8 hours. The distilled aqueous solution is stored in another container, and the dregs are used for later use; , stirred at 50° C. for 1 hour, refrigerated overnight, filtered, dried at 40° C., and pulverized into fine powder to obtain 12.5 g of beta-cyclodextrin inclusions.

[0052](2) Add water to the buffalo horn and decoct for 3 hours first, then decoct with distilled medicinal residues and Scutellaria baicalensis and other four flavors with water for two times, each time for 1 hour, combine the decoction, filter, and comb...

Embodiment 3

[0055] A kind of effervescent tablet of children's heat and speed clearing and preparation method thereof, be made of following raw material: (by grams)

[0056] Bupleurum 1250g Scutellaria baicalensis 625g Radix isatidis 1250g Pueraria 625g Honeysuckle 937.5g Buffalo horn 312.5g

[0057] Forsythia 750g Rhubarb 312.5g

[0058] Preparation:

[0059] (1) Bupleurum, honeysuckle, and forsythia add 8 times of water to distill and extract the volatile oil for 8 hours. The distilled aqueous solution is stored in another container, and the dregs are used for later use; , stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain 20 g of beta-cyclodextrin inclusions.

[0060] (2) Add water to the buffalo horn and decoct for 3 hours first, then decoct with distilled medicinal residues and Scutellaria baicalensis and other four flavors with water for two times, each time for 1 hour, combine the decoction, filter, and combine t...

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PUM

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Abstract

The invention relates to an effervescent tablet for quickly allaying infantile fever and its preparation method, wherein the effervescent tablets comprise concrete powder for reducing cold and fever for children, beta-cyclodextrin inclusion, acid agent, alkaline agent, sweetener, bulking agent and lubricating agent.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and more specifically relates to an effervescent tablet of children's resuqing and a preparation method thereof. Background technique [0002] The original preparation Xiaoer Resuqing oral liquid is used for children with exogenous high fever, headache, sore throat, nasal congestion, runny nose, cough, and dry stool. It has good curative effect and is very popular among patients. All inconvenient, mouthfeel is also bad, and also may infect bacterium and produce acid and produce gas and cause problems such as explosion, have limited its use. [0003] Xiaoer Resuqing Effervescent Tablets are effervescent tablets made by reforming the original dosage form of Xiaoer Resuqing Oral Liquid. Oral effervescent tablet is a new type of immediate-release tablet with effervescent agent as disintegrating agent. It has the advantages of being effervescently dissolved in hot water and direct...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/233A61K36/539A61K36/31A61K36/355A61K35/32A61K36/634A61K36/708A61K9/20A61K9/46A61P29/00A61P11/00
Inventor 张保献
Owner BEIJING INCREASE INNOVATIVE DRUG RESEARCH CO LTD
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