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Effervescent tables for treating thrombus, and its prepn. method

A technology of effervescent tablets and Xuesaitong, which is applied in the field of traditional Chinese medicine Xuesaitong effervescent tablets and its preparation, and can solve the problems of slow drug dissolution and slow disintegration

Inactive Publication Date: 2006-01-25
福寿堂制药有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For patients with cardiovascular and cerebrovascular diseases, time is life, but the original dosage form is ordinary sugar-coated tablets, which disintegrate slowly and the drug dissolves slowly. needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 50g of panax notoginseng saponins, add 216g of lactose, 8g of steviol, 52g of tartaric acid, mix, pulverize into fine powder, make soft material with ethanol, granulate (20 mesh sieve), dry at 60°C, and sizing (30 mesh sieve), Standby; take another polyethylene glycol-600024g melt, add 48g sodium bicarbonate, stir evenly, pulverize into fine powder after cooling, pass 80 mesh sieve, and mix with the above acid granules and 2g magnesium stearate (pass 80 mesh sieve) Evenly, press tablets to make 1000 tablets. Oral, 50-100mg once, 50mg / tablet, 3 times a day.

[0032] In the present invention, 95% ethanol is used to prepare soft materials, and the amount of ethanol used for granulation is 7.5% of the weight of the powder in ml / g.

Embodiment 2

[0034] Panax notoginseng saponins 40g, lactose 200g, steviol 6g, tartaric acid 45g, sodium bicarbonate 40g, polyethylene glycol 6000 20g, magnesium stearate 1g. The other steps are the same as in Example 1.

Embodiment 3

[0036] Panax notoginseng saponins 60g, lactose 225g, steviol 10g, tartaric acid 60g, sodium bicarbonate 55g, polyethylene glycol 6000 30g, magnesium stearate 3g.

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PUM

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Abstract

A medicine Xuesaitong in the form of effervescent tablet for treating thrombus is proportionally prepared from arasaponin, lactose, rebaudiose, tartaric acid, sodium dicarbonate, phlyethanediol, and magnesium stearate. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine Xuesaitong effervescent tablet and a preparation method thereof. Background technique [0002] The existing products on the market are Xuesaitong Tablets, which can promote blood circulation, remove blood stasis, clear the veins and activate collaterals, inhibit platelet aggregation and increase cerebral blood flow. It is used for cerebral stasis, stroke hemiplegia, heart stasis, chest pain and pain; The sequelae of vascular disease, coronary heart disease and angina pectoris belong to the above-mentioned syndromes. For patients with cardiovascular and cerebrovascular diseases, time is life, but the original dosage form is ordinary sugar-coated tablets, which disintegrate slowly and dissolve slowly. However, the original products are far from satisfying the needs of cardiovascular and cerebrovascular patients who want the drug to take effect quickly Demand. Therefore, the original products need to be i...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K31/704A61K9/20A61K9/46A61P9/10A61P7/02
Inventor 胡起玮
Owner 福寿堂制药有限公司
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