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Gentongping dripping pill for treating wind-cold channel blocking and its preparing method

A technology to block collaterals and wind-cold. It can be used in medical preparations containing active ingredients, pill delivery, bone diseases, etc. It can solve problems such as bioavailability of liver and intestine first-pass effect, which is not conducive to improving the ability of patients to seek medical treatment, and physical harm to staff. , to achieve the effect of improving bioavailability, drug safety, and low labor intensity

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0012] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0036] Now with several groups of specific examples, the preparation method of Gentongping dripping pills of the present invention will be further described.

[0037] [Group 1: Trials with a single substrate]

[0038] 1. According to the [Appendix], the dry powder containing the active pharmaceutical ingredients of 12 traditional Chinese medicines such as Shenjincao was first prepared for use;

[0039] 2. Substrate - polyethylene glycol (1000~20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0040] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:9;

[0041] 4. Then prepare according to the process of [Preparation Method] 4-7, that is, Gentongping dripping pills of various specifications can be prepared.

[0042] [test results]

[0043]Experiment 1: In order to observe the difference in quality of the Gentongping dripping pill...

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PUM

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Abstract

The Gentongping dripping pill is a kind of oral medicine composition preparation for treating cervical spondylosis caused by channel blocking wind and cold. It has high bioavailability, fast medicine release, fast acting, high effective component content, low cost and less toxic side effect, and the production process has no pollution. The Gentongping dripping pill contains the extracted effective components of 12 kinds of Chinese medicinal materials, including buck grass, white peony root, wolfberry fruit, teasel root, rehmannia root, etc. and matrix carrier.

Description

technical field [0001] The present invention relates to a kind of medicine composition which has the functions of invigorating blood circulation, dredging collaterals and relieving pain, and is used for the treatment of cervical spondylosis caused by wind-cold blocking collaterals. A pharmaceutical composition prepared from the extracts of 12 traditional Chinese medicine active pharmaceutical ingredients such as peony root, dog ridge, diapsis, rehmannia glutinosa, safflower, frankincense, myrrh, peach kernel, achyranthes bidentata, kudzu root, licorice, etc. preparation. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-10252 (ZD-0252)-2002, Gentongping Tablets have the functions of promoting blood circulation, dredging collaterals and relieving pain. Tablet preparations for the treatment of cervical spondylosis caused by wind-cold blockage, symptoms such as shoulder and neck pain, movement obstruction, uppe...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P19/08A61P29/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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