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Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs

A technology of thermotherapy, organs, applied in the direction of heating appliances for therapeutic treatments, cooling appliances for therapeutic treatments, treatments, etc.

Inactive Publication Date: 2005-09-14
CELSION CANADA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0014] While the above assignee's method non-invasively removes cysts from breast tissue, other problems arise due to the externally focused microwaves and mechanical pressure used to compress the breast tissue

Method used

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  • Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs
  • Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs
  • Thermotherapy method for treatment and prevention of breast cancer and cancer in other organs

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Embodiment Construction

[0042]DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT

[0043] Dielectric Properties of Breast Tissue

[0044] figure 1 A detailed lateral view of the female breast is shown ("Mammography-A User's Guide", National Council on Radiation Protection and Measurements, NCRP Report No. 85, 1 August 1987, p. 6). The amount of glandular and adipose tissue in the breast can vary widely, from predominantly adipose to very densely glandular. Breast cancer cells (high water content cells) often form in milk ducts and lobules of glandular tissue, such as figure 2 Shown (modified from Dr. Susan Love's Breast Book, Addison Wesley, MA, 1990, pp. 191-196). The first sign of abnormal cell growth in the tube is called intratubular hyperplasia, followed by atypical (withatipia) intratubular hyperplasia. When the duct becomes nearly full, the condition is called intraductal carcinoma in situ (DCIS). These three conditions are called precancerous conditions. Finally, when the ductal cancer...

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Abstract

A method of treating cancerous or benign organ disorders by selectively irradiating organ tissue with focused energy is disclosed. The method comprises the steps of: inserting an E-field probe sensor at an appropriate depth in the organ tissue, monitoring the temperature of the skin surface near the organ (if focused energy is used), placing two or more energy applicators around the organ, Set the initial power level delivered to each energy applicator, set the initial relative phase delivered to each energy applicator to focus energy on the E-field detector located in the organ tissue (if focused energy is used) , delivering energy to two or more energy applicators to selectively irradiate organ tissue and treat at least one cancerous and benign organ condition with focused energy, adjusting delivery to each energy applicator based on monitored skin temperature during treatment monitor the energy delivered to the energy applicator, measure the total energy delivered to the energy applicator during treatment and display the total energy in real time, and deliver the desired total energy dose through the energy applicator Treatment is complete upon delivery to the organ. Focused or unfocused energy can be used as a preferred energy source with a microwave energy applicator. However, any combination of energy applicators such as electromagnetic, ultrasonic, radiofrequency, and laser may be used together to form focused energy. Unfocused energy can be combined with focused energy to enhance thermotherapy. Several applications for breast cancer treatment include treatment of advanced and early breast cancer, prevention of breast cancer, and treatment of benign breast disease and ductal carcinoma in situ.

Description

Background of the invention [0001] In general, the present invention relates to minimally invasive methods for administering focused energy, such as adaptive microwave phased array hyperthermia, which can be used to treat ductal and adenocarcinomas and intraductal hyperplasia in flat breast tissue, as well as benign lesions Such as fibroadenomas and cysts. Additionally, methods according to the invention can be used to treat healthy tissue containing undetected microscopically pathologically altered cells with high water content, thereby preventing the occurrence or recurrence of cancerous, precancerous, or benign breast lesions. [0002] In order to treat primary breast cancer with hyperthermia, a large volume of tissue must be heated, such as a quarter or more of the breast. It is well known that approximately 90% of all breast cancers originate in ductal tissue (milk ducts), with the remainder mostly originating in lobules of glandular tissue (milk bags) (Harris et al., Th...

Claims

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Application Information

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IPC IPC(8): A61N1/40A61F7/00A61K45/00A61K48/00A61N5/02A61N5/06
CPCA61N5/02
Inventor 艾伦·J·芬恩约翰·蒙
Owner CELSION CANADA
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