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Mixtures and compounds from Antrodia camphorate myceliums and use thereof

A compound and mixture technology, applied in medical preparations containing active ingredients, drug combinations, organic chemistry, etc., can solve problems such as expensive, rare, pharmacological or clinical research

Inactive Publication Date: 2005-09-14
SIMPSON BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, few pharmacological or clinical studies have appeared in the literature to date
Because of its strict host specificity and its rarity in nature, as well as the failure of artificial cultivation, "Antrodia cinnamomea" is very expensive in Taiwan

Method used

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  • Mixtures and compounds from Antrodia camphorate myceliums and use thereof
  • Mixtures and compounds from Antrodia camphorate myceliums and use thereof
  • Mixtures and compounds from Antrodia camphorate myceliums and use thereof

Examples

Experimental program
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Effect test

Embodiment

[0032] The following examples are non-limiting and merely represent various aspects and characteristics of the invention.

[0033] General Experimental Procedure

[0034] Melting points were measured with a Yanagimoto mini hot stage melting point apparatus and were uncorrected. Optical rotation was measured with a JascoDIP-360 automatic polarimeter. UV spectra were measured with a Shimadzu UV-2200 self-recording spectrophotometer. Infrared spectra were measured with a Jasco FT / IR-230 infrared spectrometer. Measured with a Varian Unity Plus 500 spectrometer 1 H-and 13 C-NMR spectrum. EIMS and HR-EIMS were measured with a JeolJMS-AX 505 HAD mass spectrometer at an ionization voltage of 70eV. Column chromatography was performed using silica gel of BW-820MH (normal phase) and Chromatorex-ODS DM1020T (reverse phase) (Fuji Silysia).

[0035] Extraction and Separation

[0036] Under reflux, Antrodia camphorata mycelium powder (60 g) from Taiwan Shansheng Biotechnology Co., Lt...

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Abstract

This invention relates to a new compound from Antrodia Camphorata and maleic acid of maleic acid and amber acid, and its medicine use. This invention relates to the mycelium and combination which includes compound in this invention.

Description

technical field [0001] The present invention relates to novel mixtures and compounds derived from the mycelium of Antrodia Camphorata and their use. The present invention relates to a composition or mycelium comprising a compound of the present invention. Background technique [0002] In Taiwan, the fruiting body of Antrodia camphorata (Polyporaceae, Aphyllophorales) is well known as a traditional Chinese medicine. It grows only in the inner layer of the heartwood wall of the endemic Taiwanese evergreen Cinnamomun kanehirai (Hay) (Lauraceae). It is rare and not cultivated. The fruiting body has been used to treat food and drug poisoning, diarrhea, abdominal pain, hypertension, skin mange and liver cancer. Few biological activity studies have been reported to date. [0003] In Taiwan, Antrodia Cinnamomea, also known as Antrodia cinnamomea, has recently been reported as a new fungal species characterized by the cylindrical shape of its basidiospores present in the fruiting...

Claims

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Application Information

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IPC IPC(8): A61K31/4015A61P1/16A61P3/06A61P9/12A61P29/00A61P35/00C07D207/456C07D307/60
Inventor 服部征雄许嘉钦
Owner SIMPSON BIOTECH CO LTD
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