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Pharmaceutical composition, its preparation and usage

A technology of composition and medicine, which is applied in the field of traditional Chinese medicine preparations and its preparation, can solve the problems of inability to treat both symptoms and root causes, poor disease resistance, low anti-virus ability, etc., and achieve the effect of being convenient for large-scale promotion and simple production process

Inactive Publication Date: 2005-06-22
成都三明药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above can only temporarily control the disease and treat superficial symptoms, and cannot achieve the effect of treating both symptoms and root causes.
Moreover, long-term use of western medicine will produce side effects that lead to imbalance of yin and yang in the human body, resulting in dependence, and endocrine disorders may also occur, which will reduce the body's immunity, lower the body's anti-virus ability, and poor disease resistance, making the disease repeatedly difficult to heal and eventually tend to deteriorate. complication

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 Preparation of Extract

[0026] ①Preparation of Codonopsis Codonopsis extract: reflux extraction of Codonopsis pilosula with 10 times the amount of 50%-80% ethanol, recover ethanol, add the concentrated solution to D101 macroporous resin column, elute with water first, then elute with 10%-50% ethanol, Collect the ethanol eluate; recover the ethanol from the ethanol eluate until it has no alcohol smell, and obtain the Codonopsis pilosula extract, which is spray-dried.

[0027] ②Extraction of volatile oil of Nardinus: add 10 times the amount of drinking water to Nizhny pine, extract the volatile oil according to steam distillation, collect the volatile oil for later use.

[0028] ③ Extraction of volatile oil from dried ginger: Add 10 times the amount of drinking water to dried ginger, extract volatile oil according to steam distillation, collect volatile oil, and set aside.

Embodiment 2

[0029] The preparation of embodiment 2 soft capsules

[0030] ①Preparation of capsule shell

[0031] The raw materials of the capsule shell include glue, plasticizer, water and additives, the ratio of which is 1:0.3-0.8:0.5-1.2:0.001-0.01. The rubber material can be gelatin and gum arabic; the plasticizer can be glycerin and sorbitol; the additive is mainly a preservative, which can be ethyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, or propyl p-hydroxybenzoate.

[0032] ②Selection of dispersion medium

[0033] One or more of edible oil, soybean oil, peanut oil and polyethylene glycol can be selected as the dispersion medium.

[0034] ③ Selection of accessories

[0035] Excipients may include wetting agents and suspending agents. Wetting agents may include Tweens and Spans, and suspending agents may include beeswax, aluminum monostearate, ethyl cellulose, etc.

[0036] ④Steps:

[0037] a, earlier beeswax: the mixture 80g of ethyl cellulose (1:2) is added in 800ml soybea...

Embodiment 3

[0040] Example 3 Preparation of sugar-free granules

[0041] ① Add 100g of β-cyclodextrin to the volatile oil of nard pine and dried ginger, ultrasonically clathrate at 40-60°C for 30 minutes, filter with suction, dry at 40-60°C for 6 hours, and set aside.

[0042] ②Codonopsis pilosula extract, add 100g of starch, 50g of protein sugar and the inclusion compound of the above-mentioned volatile oil, wet granulate, and divide into packages.

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PUM

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Abstract

The invention provides a Chinese medicinal composition for treating spleen and stomach diseases, which is prepared from Codonopsis pilosula extract, spikenard volatile oil, dried ginger volatile oil as raw material, wherein the composition contains pilose asiabell root glycoside I, the invention also provides the method for preparation and use of the pharmaceutical composition.

Description

technical field [0001] The invention relates to a medicine for treating gastropathy of spleen-stomach qi deficiency combined with stagnation of qi and a preparation method thereof, in particular to a traditional Chinese medicine preparation and a preparation method thereof. Background technique [0002] TCM dialectical classification divides stomach diseases into liver-stomach incompatibility type, spleen-stomach deficiency-cold type, and stomach-yin deficiency type, among which the spleen-stomach deficiency-cold type is further divided into two subtypes: simple deficiency-cold type and middle-deficiency Qi stagnation type, which are currently used to treat There are many Chinese patent medicines for stomach problems, such as Xiangsha Yangwei Capsules, Jianwei Pills, Kuaiwei Tablets, Sanjiuweitai Granules, Xiaobanxia Mixture, and Zhonglipi Pills, etc. It is rarely used to treat spleen and stomach Qi deficiency combined with Qi stagnation. Xiangsha Liujun Pills are composed ...

Claims

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Application Information

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IPC IPC(8): A61P1/04A61P1/14
Inventor 阳向波李世娟罗丽丹谢炜
Owner 成都三明药物研究所
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