Externally applied pharmaceutical composition and application

Abstract

The invention relates to an externally applied pharmaceutical composition and application, wherein the composition comprises sodium silicate 25-100 parts, glacial acetic acid 25-50 parts, and various dermatosis-treating medicaments. The composition has the advantages of high bioavailability and short course of treatment.

Description

Technical field: [0001] The invention relates to a drug carrier composition and a preparation method for treating skin diseases. technical background [0002] There are many types of skin diseases with complex etiology. The pathogenesis of various skin diseases is still not clear so far. The symptoms are stubborn and difficult to heal. The treatment is mainly for single symptoms, such as eczema, sweat rash, diaper dermatitis, seborrheic dermatitis , skin itching, beriberi, female vaginal itching, bacterial vaginosis, etc., these various skin diseases have two common pathologies (1) due to the overflow of sebum secretions, secondary skin inflammation , both due to the increase in sebum secretion and the change of chemical composition, the normal flora on the skin surface multiply and become opportunistic pathogens, which invade the skin to form. (2) The sweat glands are not smooth, the skin cannot breathe normally, and the excess water under the skin cannot be normally secre...

AI Technical Summary

Problems solved by technology

The traditional treatment methods for these skin diseases are to take symptomatic drugs orally and to smear various therapeutic ointments on the skin surface of the lesions, and the base fats of the various ointments are two manufacturing methods: water-in-oil W / O or oil-in-water O / W is absolutely nothing else, the base fats of these two pastes are base fats formed by the emulsification of oil and water, both of which contain oil components, and the common symptom of skin diseases is that the sweat glands are not smooth, It is caused by bacteria infiltrating the skin. According to the theory of traditional Chinese medicine, "if it doesn't work, it will cause pain" and the oil contained in the ointment will form a seal on the surface of the skin. Even if the ointment contains "no matter how effective medicine" it will affect the treatment Effect

[0003] Chinese patent CN 1064614A discloses a kind of wet prickly heat cream, the composition is sodium silicate and hydrochloric acid to make silica gel cream, it uses silica gel directly to have very strong adsorption force, produces drying effect to the skin of human body, thereby achieves the purpose of treatment , the scope of this medicine is limited, only for eczema of the human body, and its manufacturing method is to neutralize under strong stirring with colorless transparent sodium silicate and reagent hydrochloric acid, let cool, centrifuge and wash the silica gel cream that is made, using Corrosive strong hydrochloric acid, synthetic silica gel that is insoluble in water and any solvent, and using a large amount of deionized water to remove chloride ions in the centrifugation and washing process, the cost is high