Freeze-dried powder injection of Tianjihuang and its making method

Abstract

A Chinese medicine 'freeze-dried Japanese St, John's-wort powder injection' is prepared from Japanese St. John's-wort herb through extracting its active component, mixing with the additive for injection, stirring, adding water for injection, regulating pH=4.0-8.0, removing heat source, aseptic filtering and freeze drying.

Description

technical field [0001] The invention relates to a Tianjihuang freeze-dried powder for injection and a preparation method thereof, belonging to the medicine [0002] technology field. Background technique [0003] Tianjihuang is the dried whole herb of Garcinia fruticosa, bitter, pungent and flat in nature and taste, and returns to the liver meridian. It has the effects of clearing away heat and dampness, reducing swelling and detoxification. Bite embolism. Clinically, the preparation of Tian Jihuang is mainly injection, which was recorded in the Pharmacopoeia of the People's Republic of China in 1977. It is widely used clinically to treat acute viral hepatitis caused by excess liver and gallbladder. It is an ideal medicine for emergency in traditional Chinese medicine. However, in the production process, manufacturers generally reported that the product has poor stability, and long-term storage is prone to precipitation, and the batch pass rate is low, making it difficult ...

AI Technical Summary

Problems solved by technology

However, in the production process, manufacturers generally report that the product has poor stability, long-term storage is prone to precipitation, and the batch pass rate is low. It is difficult to put it into industrialized production on a large scale, which brings inconvenience to the wide application in clinical practice.