Application of Naoxintong preparation in preparation of medicine for treating non-alcoholic fatty liver disease

Abstract

The invention discloses a new medicinal application of a Naoxintong preparation, and particularly relates to an application of the Naoxintong preparation in preparation of a medicine for treating non-alcoholic fatty liver. Experiments prove that the Naoxintong preparation can significantly reduce the body weight, liver weight / body weight index and liver lipid deposition of non-alcoholic fatty liver model animals, significantly improve liver function indexes including aspartate transaminase (AST) and glutamic-pyruvic transaminase (ALT), significantly reduce the levels of triglyceride (TG), cholesterol (TC) and low density lipoprotein (LDL-C) in serum in vivo, and significantly improve the liver function indexes of non-alcoholic fatty liver model animals. The traditional Chinese medicine composition has a remarkable effect on treating the non-alcoholic fatty liver disease. The medicinal range of the Naoxintong preparation is further expanded.

Description

technical field [0001] The invention relates to a new medicine application of Naoxintong preparation, especially the application in preparing medicine for treating non-alcoholic fatty liver. Background technique [0002] Non-alcoholic fatty liver disease (Non-alcoholic Fatty Liver Disease, NAFLD) refers to the clinical chronic liver disease caused by excluding alcohol and other liver damage factors, with excessive fat deposition in liver cells as the key pathological feature, including simple fatty liver , nonalcoholic steatohepatitis, liver fibrosis, cirrhosis, and hepatocellular carcinoma. At present, with the increase in the obesity rate of the global population, the global incidence of NAFLD is as high as 18-30%, and the risk of complications such as cardiovascular and cerebrovascular diseases and type 2 diabetes is increasing year by year, which seriously threatens human health. At the same time, the pathogenesis of NAFLD is complex and there are multiple pathogenic fa...

AI Technical Summary

Problems solved by technology

At the same time, the pathogenesis of NAFLD is complex, and there are multiple pathogenic factors, which have a serious impact on the quality of life and life expectancy of patients.

[0003] At present, modern medicine mostly uses exercise and weight loss as the main treatment for NAFLD. Chemical drugs, such as lipid-lowering and blood-sugar-lowering drugs, need to be taken for a long time, and are prone to adverse reactions such as liver and kidney damage, and their clinical application is limited.

Images