Composition for treating hormone face and acne skin and preparation method thereof

A composition and acne technology, applied in the field of biology and new medicine, can solve the problems of poor treatment effect, lack of pertinence, long treatment time, etc., to enhance skin nutrition and water intake, reduce skin fine lines, Improvement effect of inflammatory skin

Inactive Publication Date: 2022-01-28
奥瑞京生物科技(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of the compositions on the market for the treatment of acne-prone skin and hormonal face are not individually targeted, the treatment time is long, the treatment effect is not good, and it is easy to repeat after treatment

Method used

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  • Composition for treating hormone face and acne skin and preparation method thereof
  • Composition for treating hormone face and acne skin and preparation method thereof
  • Composition for treating hormone face and acne skin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Preparation of Stem Cell Culture Supernatant

[0033] The stem cell culture supernatant was prepared from the umbilical cord, which was taken from the puerpera. The specific requirements for the puerpera are: (1) 36-42 weeks of pregnancy, normal development and nutrition; (2) no infectious diseases, a tube of 5mL maternal blood is required , Maternal blood test, EBV, HCMV, HIV, HBV, HCV, syphilis should be negative; (3) no malignant tumor; (4) no serious complications during pregnancy; (5) no family history of genetic diseases.

[0034] The umbilical cord obtained by the invention is uniform in appearance, smooth in surface, free of transparent colloid, free of wrinkle or edema, and elastic.

[0035] Clean and disinfect the biological safety cabinet according to the management regulations of aseptic technology, prepare the reagents and materials required for the experiment, wipe the outer surface of the bottle with 75% alcohol from the bottle cap down, and put...

Embodiment 2

[0056] Embodiment 2 is used for the preparation of the composition of treatment hormone face and acne muscle

[0057] In an environment of Class A cleanliness, the hyaluronic acid, glycerin, vitamin B, trehalose, and stem cell culture supernatant are respectively in accordance with the mass percentage: 1-3%, 2-6%, 0.1-2%, 2-20% %, 20-30% are calculated and weighed, and sterilized water for injection makes up 100%; then, after the above components are fully mixed, they are aseptically filled into 2ml sterile tubes without pyrogens.

Embodiment 3

[0058] The effect test of embodiment 3 composition

[0059] Randomly select 20 patients with hormonal face and acne skin that are difficult to be cured by existing methods, firstly disinfect the rolling needle with 75% alcohol (time: ≥20min), clean the face, use povidone iodine to disinfect the face, and then use normal saline Wipe clean. Those who are sensitive to pain can use anesthetics to apply on the face (but anesthetics can cause allergies, burn the skin, and affect skin metabolism), and then perform composition care after the facial acne is treated.

[0060] Use a roller needle to gently walk the empty needle on the face, and then apply the composition evenly on the face (apply in different areas, do not apply at one time) and start rolling. The rolled areas are divided into: forehead, cheeks, and chin. The direction of the needle rolling is in the shape of a rice, that is, horizontal, vertical and diagonal. 4-5 times in each direction, with moderate or mild strength...

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Abstract

The invention belongs to the technical field of biology and new medicine, and particularly relates to a composition for treating hormone face and acne skin, the composition comprises the following active ingredients: hyaluronic acid, glycerol, vitamin B, trehalose and stem cell culture supernatant, and the stem cell culture supernatant is derived from human umbilical cord mesenchymal stem cells. The preparation method of the composition comprises the following steps: (1) calculating and weighing the hyaluronic acid, the glycerol, the vitamin B, the trehalose and the stem cell culture supernatant according to the mass percentage contents of 1 to 3%, 2 to 6%, 0.1 to 2%, 2 to 20% and 20 to 30% respectively, and supplementing the balance of sterilized water for injection to 100%; and (2) fully mixing the components, and aseptically filling the mixture into a 2ml sterile heat-source-free pipe. The invention has the beneficial effects that the product takes effect for a short time, can treat various skin problems, and is high in effective rate and not easy to relapse.

Description

technical field [0001] The invention belongs to the technical field of biology and new medicine, and in particular relates to a composition for treating hormone face and acne skin and a preparation method thereof. Background technique [0002] Hormone face, the scientific name is hormone-dependent dermatitis, is caused by long-term improper use of hormone-containing skin care products or drugs on the face. The main symptoms are large flushing patches on the face, with obvious borders, pink to dark red in color, papules, blisters on the surface of the erythema, pustules and oozing in severe cases, skin atrophy and thinning at the erythema , obvious red blood streaks can be seen, accompanied by obvious burning and itching, and severe cases may have obvious pain. The skin of this disease is relatively sensitive. After eating spicy and stimulating food, excitement, heat or skin care products that are intolerable to the skin, the skin will turn red obviously, and the discomfort ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/28A61K31/728A61K9/00A61K47/26A61K47/10A61P17/00A61P17/10C12N5/0775
CPCA61K35/28A61K31/728A61K9/0021A61K47/26A61K47/10A61P17/00A61P17/10C12N5/0665C12N2509/00C12N2509/10A61K2300/00
Inventor 杜焕青沈继广刘云龙杨艳浩杜婷
Owner 奥瑞京生物科技(北京)有限公司
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