Ophthalmic lubricating liquid composition and application thereof

Abstract

The invention relates to an ophthalmic lubricating liquid composition and application thereof. The ophthalmic lubricating liquid composition is compounded by selecting sodium hyaluronate with different molecular weights, polyvinylpyrrolidone and polyethylene glycol with a proper weight ratio are supplemented, under the synergistic effect of the components, the moisturizing and tackifying effects are achieved, the prepared lubricating liquid composition has excellent lubrication and moisture retention properties, dry eyes can be effectively inhibited, and the comfort level of wearing glasses is improved. According to the ophthalmic lubricating liquid composition, the biguanide preservative, tromethamine and edetate disodium are compounded to form a preservative system, and under the synergistic effect of the three, effective collision between the preservative and microorganisms is remarkably improved, so that the effect of effectively improving the corrosion resistance of the preservative and microorganisms can be achieved under the condition that the dosage of the biguanide preservative is not increased. Therefore, the lubricating liquid still has efficient corrosion resistance and biocompatibility.

Description

technical field [0001] The invention belongs to the technical field of contact lens lubricating fluid, and in particular relates to an ophthalmic lubricating fluid composition and an application thereof. Background technique [0002] Contact lenses are increasingly playing an important role in enhancing visual health due to their optical correction advantages, especially soft contact lenses are favored by more and more myopia patients due to their comfort and ease of use. Increase. [0003] When wearing contact lenses, two more contact surfaces are added to the eyes (from one corneal interface to three interfaces), resulting in accelerated tear evaporation and reduced tear wetting, and then the following symptoms will appear, such as: foreign body sensation and fatigue symptoms, irritation, itching, burning, increased blinking, conjunctival hyperemia, mucus discharge from the eyes, allergies to smoke, air conditioning and environmental factors, etc. According to reports, t...

AI Technical Summary

Problems solved by technology

However, for solutions with high viscosity and water-soluble substances with high water content, the antimicrobial antiseptic effect is poor, and the conventional control measures are to increase the amount of preservatives in the solution or use special preservatives

A large number of studies have shown that ocular preparations with high preservative content are prone to ocular surface toxicity and / or irritation

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