Application of ginsenoside compound K in preparation of medicine for treating diabetic kidney diseases
A technology of ginsenoside and diabetes, which is applied in the field of medicine, can solve the problems of lack of DKD and other problems, and achieve the effect of improving kidney damage
Pending Publication Date: 2021-12-17
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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However, in general, there is still a lack of effective drugs for the targeted treatment of DKD in clinical practice.
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[0036] The content of the present invention is further explained or illustrated by examples below, but these examples should not be construed as limiting the protection scope of the present invention.
[0037] It should be noted that various reagents used in the following examples are known in the art and can be obtained commercially.
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Abstract
The invention relates to an application of ginsenoside compound K or a pharmaceutically acceptable salt thereof in preparation of a medicine for treating diabetic kidney diseases.
Description
technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of ginsenoside compound K in the preparation of medicines for treating diabetic nephropathy. Background technique [0002] Diabetic kidney disease (DKD) is one of the most serious chronic complications of diabetes. Clinically, if patients with type 1 diabetes and type 2 diabetes have microalbuminuria (urine albumin-to-creatinine ratio 30-<300 mg / g) or massive albuminuria (urine albumin-to-creatinine ratio ≥ 300 mg / g) and / or estimated Glomerular permeability (eGFR) <60ml·min -1 And last for more than 3 months, it is diagnosed as DKD. Epidemiological surveys show that the prevalence of DKD in my country is 1.23%, and there are about 24 million DKD patients, and the number of new uremia patients caused by DKD reaches 990,000 each year. DKD has become the leading cause of chronic kidney disease (CKD) and an important risk factor for cardiovascular disease ...
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IPC IPC(8): A61K31/704A61P13/12A61P3/10
CPCA61K31/704A61P13/12A61P3/10
Inventor 陈倩王涛张祎刘梦扬吴昱铮王丹任东文刘洛坤
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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