Ozone liquid dressing applied to skin diseases and preparation method thereof

Abstract

The invention discloses an ozone liquid dressing applied to skin diseases and a preparation method thereof. The ozone liquid dressing is prepared from ozone oil, water, glycerol, maltitol, betaine, propylene glycol, trehalose, 1, 2-hexanediol, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, isoprene glycol, ammonium acryloyldimethyl taurate / VP copolymer, methylparaben, dipotassium glycyrrhizinate, polyacrylate cross-linked polymer-6, EDTA (ethylene diamine tetraacetic acid) disodium, an oat kernel extract, p-hydroxyacetophenone, butanediol and a Chinese herbaceous peony root extract. The prepared ozone liquid dressing is good in emulsification effect, uniform in ozone distribution and free of layering phenomenon after being placed for a long time.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to an ozone liquid dressing applied to skin diseases and a preparation method thereof. Background technique [0002] Ozone has a strong oxidation effect. Ozone molecules can directly act on the membrane proteins on the surface of bacteria and viruses to denature them, further destroying the DNA and RNA of bacteria and viruses, making them unable to replicate, thereby achieving the effect of sterilization. Because ozone has a killing effect on various bacterial propagules, spores, viruses, herpes, molds and protozoa, the high concentration of oxygen generated during the ozone decomposition process can promote the growth of granulation and the repair of damaged tissues, making it play an important role in the field of medicine. effect. [0003] After ozone dissolves in water, it will become a strong oxidant, which has a strong killing effect on living cells, but ozone is ex...

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Problems solved by technology

[0003] After ozone dissolves in water, it will become a strong oxidant, which has a strong killing effect on living cells, but ozone is extremely unstable in water. Studies have found that ozone is quite stable in monounsaturated fatty acids, and it can be used to make ozone oil. It has been stored for more than 2 years. Ozonated olive oil is the most used at present, but the price of olive oil on the market is generally expensive, and the quality varies. The duration is short, and a large amount of ozone needs to be added to obtain better results. In addition, the existing ozonated olive oil is difficult to be unacceptable due to its pungent smell, which affects the popularization and application of ozone oil and its related products.

[0004] Camellia oil is rich in unsaturated fatty acids, the content of unsaturated fatty acids exceeds 90%, which is far better than olive oil, and the molecular structure of fatty acids contained in camellia oil is mostly smaller than that of olive oil, without side effects and less greasy feeling. In practice, the ozone in the ozone oil prepared by using camellia oil as the base oil is difficult to mix evenly with the camellia oil, so that the ozone is unevenly dispersed in the camellia oil, and the pure ozone oil is mildly irritating to the intact skin , There is no obvious tingling sensation when ozone oil is applied on non-damaged skin, but there is a tingling sensation when applied to damaged skin; and some people don't like the sticky feeling of ozone oil, so in order to reduce skin irritation and stickiness It is necessary to add skin conditioning active components and water to the ozone oil, but this will cause the prepared ozone liquid to be prone to stratification, which will affect the uniformity of ozone dispersion, and then affect its therapeutic effect

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