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Platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation

A platelet-rich plasma and separation device technology, which is applied in the field of platelet-rich plasma collection and separation devices, can solve the problems of inconvenient separation, low separation efficiency, impurity of platelet-rich plasma, etc., and achieve the effect of convenient separation and short separation time

Pending Publication Date: 2021-10-01
起源细胞技术(滁州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a platelet-rich plasma collection and separation device using physical (freezing) anticoagulation to solve the problems of inconvenient separation, impurity of separated platelet-rich plasma and low separation efficiency in the background technology

Method used

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  • Platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation
  • Platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation
  • Platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation

Examples

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Effect test

Embodiment 1

[0057] A method for producing platelet-rich plasma using physical (frozen) anticoagulation, specifically comprising the following steps:

[0058] S1. Freezing, put the freezing sleeve 4 on the bottom of the outer syringe 1, pack the collection and separation device under aseptic conditions, and then sterilize it, take out the collection and separation device after a period of time in the freezing room, and the temperature of the freezing room is 20°C, the freezing time is 30 minutes;

[0059] S2. Centrifuge, take a sterilized blood collection needle with a Luer connector needle seat, remove the plugging screw cap 27 on the outer needle seat 26 of the outer syringe 1, and install the needle seat connector of the blood collection needle on the outer needle seat 26 Above, carry out routine disinfection on the arm of the human body, puncture the vein with a blood collection needle, pull the inner syringe 2 after seeing the blood return, so that the blood flows into the inside of t...

Embodiment 2

[0062] A method for producing platelet-rich plasma using physical (frozen) anticoagulation, specifically comprising the following steps:

[0063] S1. Freezing, put the freezing sleeve 4 on the bottom of the outer syringe 1, pack the collection and separation device under aseptic conditions, and then sterilize it, take out the collection and separation device after a period of time in the freezing room, and the temperature of the freezing room is 20°C, the freezing time is 30 minutes;

[0064] S2. Centrifuge, take a sterilized blood collection needle with a Luer connector needle seat, remove the plugging screw cap 27 on the outer needle seat 26 of the outer syringe 1, and install the needle seat connector of the blood collection needle on the outer needle seat 26 Above, carry out routine disinfection on the arm of the human body, puncture the vein with a blood collection needle, pull the inner syringe 2 after seeing the blood return, so that the blood flows into the inside of t...

Embodiment 3

[0069] A method for producing platelet-rich plasma using physical (frozen) anticoagulation, specifically comprising the following steps:

[0070] S1. Freezing, put the freezing sleeve 4 on the bottom of the outer syringe 1, pack the collection and separation device under aseptic conditions, and then sterilize it, take out the collection and separation device after a period of time in the freezing room, and the temperature of the freezing room is 20°C, the freezing time is 30 minutes;

[0071] S2. Centrifuge, take a sterilized blood collection needle with a Luer connector needle seat, remove the plugging screw cap 27 on the outer needle seat 26 of the outer syringe 1, and install the needle seat connector of the blood collection needle on the outer needle seat 26 Above, carry out routine disinfection on the arm of the human body, puncture the vein with a blood collection needle, pull the inner syringe 2 after seeing the blood return, so that the blood flows into the inside of t...

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Abstract

The invention relates to the technical field of medical instruments, in particular to a platelet-rich plasma collecting and separating device adopting physical (freezing) anticoagulation, which comprises a plugging screw cap and an outer injector, an inner injector is inserted in the outer injector, a piston assembly is arranged at the bottom of the inner injector and is positioned in the outer injector. A fixed anti-rotation frame is integrally formed on the top of the piston assembly. The plasma prepared by the device and the method disclosed by the invention is pure (without exogenous anticoagulant and other additives) and has different convertible use modes: the separated plasma is in a liquid state within 30 minutes at a low temperature (above a freezing temperature), the liquid plasma can be converted into jelly-shaped gel along with temperature and time changes, different clinical requirements can be met, and the application space is expanded. By utilizing the device and the method disclosed by the invention, platelet plasma or gel with different concentrations can be prepared only by strictly mastering three elements of temperature, time and centrifugal force.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a platelet-rich plasma collection and separation device using physical (freezing) anticoagulation. Background technique [0002] The blood of the human body is composed of formed components (including red blood cells, white blood cells, platelets) and liquid components (plasma). After the blood is isolated from the body, it is called whole blood. Whole blood contains a large number of coagulation factors, including coagulation factor Ⅰ (fibrinogen), Coagulation factor II (prothrombin), coagulation factor III (tissue factor), coagulation factor IV (calcium ion), coagulation factor V (thrombinogen) and so on. There are two activation systems in the human body, endogenous and exogenous. The former refers to the damage of the cardiovascular intima, or the activation of factor XII through contact with abnormal surfaces when blood flows out of the body. The latter activates f...

Claims

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Application Information

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IPC IPC(8): A61M1/00B04B5/04
CPCB04B5/0421A61M2202/0413A61M2202/0014
Inventor 杨浩
Owner 起源细胞技术(滁州)有限公司
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