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Iron-based metal organic framework material as well as preparation and application thereof

An organic framework, iron-based metal technology, applied in the direction of analysis by chemical reaction of materials, material analysis by observing the effect on chemical indicators, color/spectral property measurement, etc., can solve difficult modification, low catalytic performance, etc. , Insufficient types of nanozymes, etc.

Active Publication Date: 2021-07-16
EAST CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the fly in the ointment is that the types of nanozymes reported so far are far from enough, and some materials have relatively low catalytic performance and are not easy to be modified.

Method used

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  • Iron-based metal organic framework material as well as preparation and application thereof
  • Iron-based metal organic framework material as well as preparation and application thereof
  • Iron-based metal organic framework material as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Preparation of Fe-MOFs: Based on the research on Fe-MOFs synthesis methods and nanozyme functionalization in some literatures, a certain amount of 3,5 - Dicarboxyphenylboronic acid and ferric chloride hexahydrate were dissolved in 15mL of DMF, then acetic acid was added to the mixed solution to adjust, and finally the mixed solution was placed in an oil bath at 120°C for 12 hours, and the reaction time obtained by different monitoring Product, the specific consumption is shown in Table 1. After the reaction, cool to room temperature, collect the product after centrifugation, and wash with DMF and ethanol three times by repeated centrifugation. The obtained solid was placed in a vacuum drying oven and dried under vacuum at 60° C. for one day to obtain Fe-MOFs solid powder.

[0047] Such as figure 2 with 3 As shown, during the synthesis process, the present invention found that adjusting the acidity and alkalinity of the solvent has a great influence on the shape and ...

Embodiment 2

[0052] Research on the properties of Fe-MOFs peroxidase: In the present invention, the simple classic reaction of hydrogen peroxide and peroxidase to oxidize TMB is used to investigate the peroxidase activity of Fe-MOFs. Such as Image 6 As shown, when Fe-MOFs were not added to the system, the efficiency of TMB oxidation by hydrogen peroxide was very low (such as Image 6 (b)); while in the presence of Fe-MOFs, TMB was rapidly oxidized by hydrogen peroxide to blue and exhibited the characteristic absorption peak of oxidized TMB (oxTMB) at 652nm (such as Image 6 (c)). This experimental result successfully determined the mimic peroxidase activity of Fe-MOFs.

[0053] In addition, in order to further study the catalytic activity and kinetic parameters of Fe-MOFs, TMB and H 2 o 2 Related experiments were carried out as substrates for the determination of apparent steady-state kinetics. Kinetic data were obtained by fixing the concentration of one substrate and varying the othe...

Embodiment 3

[0057] Fe-MOFs for the detection of F - The experiment: in H 2 o 2 In the presence of Fe-MOFs added to the TMB system, the color changes obviously, indicating that TMB is catalyzed and oxidized. When adding F to the system - , Fe-MOFs and F - specific recognition and Fe 3+ with F - The combination of leads to the collapse of the skeleton ( Figure 8 A and B), which in turn leads to the catalytic H 2 o 2 The ability to oxidize TMB is weakened. Therefore, the oxidation process of TMB is effectively inhibited, the color of the system becomes light blue, and the absorbance decreases, that is, F - It has a great inhibitory effect on the mimic enzyme activity of Fe-MOFs (such as Figure 9 shown). In view of this, the present invention has developed a method for detecting F - colorimetric sensing. Since biological samples with complex compositions are often faced in practical analytical applications, it is critical to evaluate the selectivity of the method. Therefore, s...

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Abstract

The invention belongs to the field of environmental monitoring, and discloses an iron-based metal organic framework material Fe-MOFs and a synthesis method thereof. 3,5-dicarboxyphenylboronic acid is used as a ligand to be assembled with metal iron ions, and the iron-based metal organic framework material (Fe-MOFs) with boric acid functionalization is obtained under the action of a regulator. A research result shows that the Fe-MOFs nano material shows excellent peroxidase mimetic property. In the presence of hydrogen peroxide, the Fe-MOFs can catalytically oxidize colorless 3,3',5,5'-tetramethylbenzidine (TMB) to show a blue color. Meanwhile, when fluorine ions exist in the system, the peroxidase property of the Fe-MOFs is inhibited based on the specific recognition of boric acid on the fluorine ions and the strong interaction between metal ions and the fluorine ions. On the basis, the invention constructs a novel method for colorimetric detection of fluorine ions. The method has relatively high selectivity and sensitivity on detection of the fluorine ions, and has great application potential on visual detection of the fluorine ions in environmental monitoring.

Description

technical field [0001] The invention belongs to the field of environmental monitoring, and relates to the preparation and application of iron-based metal organic framework materials, in particular to a 3,5 - Dicarboxyphenylboronic acid as ligand and Fe 3+ Method for preparing new iron-based metal-organic frameworks (Fe-MOFs) with peroxide-mimetic enzyme properties and its application in environmental water samples for F - detection. Background technique [0002] Fluoride ion is an essential trace element for the human body, and has a great effect on the organism. Its physiological functions on the human body are mainly in the formation and metabolism of teeth and bones. It widely exists in the surface, coal, water and ore. If the fluorine content in coal and ore is too high, it will have an adverse effect on human health and life. For example, during the coal combustion process, it is discharged into the environment in the form of silicon tetrafluoride, and enters the wa...

Claims

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Application Information

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IPC IPC(8): C08G83/00G01N21/78G01N21/31
CPCC08G83/008G01N21/78G01N21/31
Inventor 张翠玲鲜跃仲侯冬艳
Owner EAST CHINA NORMAL UNIVERSITY
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