Silicone hydrogel with high oxygen permeability, corneal contact lens and preparation method of corneal contact lens

Abstract

The invention discloses a silicon hydrogel. The silicon hydrogel is prepared from the following components in parts by mass through a polymerization reaction: 5 to 60 parts of a single-terminated organosiloxane macromonomer, 0.5 to 10 parts of a double-terminated organosiloxane macromonomer, 0 to 30 parts of other silicon-containing monomers, 5 to 70 parts of a hydrophilic monomer, an initiator and a cross-linking agent. According to the invention, the single-terminated organosiloxane macromonomer is taken as a main component and compounded with the double-terminated organosiloxane macromonomer, and the single-terminated organosiloxane macromonomer and the double-terminated organosiloxane macromonomer are compounded to generate an obvious synergistic effect, so the oxygen permeability, the mechanical property and the hydrophilic property of the silicon hydrogel can be better improved. The invention also discloses a corneal contact lens prepared from the silicone hydrogel. The corneal contact lens has the advantages of high oxygen permeability, good light transmission, strong hydrophilicity, good mechanical properties and comfortable wearing, does not contain a solvent, and is beneficial to large-scale industrial production.

Description

technical field [0001] The invention relates to a silicon hydrogel material, in particular to a highly oxygen-permeable silicon hydrogel, a corneal contact lens and a preparation method thereof, belonging to the field of contact lens lens material preparation. Background technique [0002] Contact lenses, also known as contact lenses, are used to correct vision, protect eyeballs or increase the aesthetic feeling of eyes, and are favored by people. The field of contact lenses has high requirements on the oxygen permeability of materials. If oxygen cannot be supplied normally during contact lens wearing, the cornea will be hypoxic. Long-term insufficient oxygen supply will cause thinning of the corneal epithelium and dry eyes. With the development of science and technology, contact lenses have gradually developed from early hard materials to soft materials with better comfort. Soft contact lenses, also known as hydrogel contact lenses, have good chemical stability, biocompati...

AI Technical Summary

Problems solved by technology

However, due to the high hydrophobicity of PDMS, the compatibility with hydrophilic monomers is poor, and the addition amount is limited, which limits the improvement of the oxygen permeability value of the material; and the obtained silicone hydrogel has a strong surface hydrophobicity, which affects the performance of the lens. Wearing comfort

In order to increase the amount of PDMS added, and then increase the oxygen permeability of the material, suitable organic solvents are added to the formula as simple solubilizing agents. An appropriate amount of solvents can indeed improve the compatibility, but the addition of solvents also destroys The original network structure of the material is reduced, which reduces the strength and toughness of the finished lens. At the same time, during the polymerization production process, the solvent will volatilize a large amount into the air, which may easily cause fire and explosion, and increase the danger of production operation.

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