Automatic cerebrospinal fluid cell analysis system based on artificial intelligence

An automatic analysis system and artificial intelligence technology, applied in the field of cerebrospinal fluid cytology detection, can solve the problem of cerebrospinal fluid cell identification errors, etc., and achieve the effect of reducing manual labor intensity and improving work efficiency

Inactive Publication Date: 2021-04-02
GENERAL HOSPITAL OF NINGXIA MEDICAL UNIV +2
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Problems solved by technology

During the test of the above-mentioned device, due to the difference in the structure, shape, texture and size of the cell surface and nucleus, the scattered light measured at different angles will be different, which may easily lead to misidentification of cerebrospinal fluid cells

Method used

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  • Automatic cerebrospinal fluid cell analysis system based on artificial intelligence
  • Automatic cerebrospinal fluid cell analysis system based on artificial intelligence
  • Automatic cerebrospinal fluid cell analysis system based on artificial intelligence

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specific Embodiment approach

[0054] An automatic analysis system for cerebrospinal fluid cells based on artificial intelligence. The system includes three parts: a method for establishing a cerebrospinal fluid cell image feature library; a method and device for collecting cerebrospinal fluid cell image features; and a method for automatic recognition and counting of cerebrospinal fluid cell images.

[0055] (1) cerebrospinal fluid cell image feature library and its establishment method, comprising the following steps (see figure 1 ):

[0056] Step 1: Prepare cerebrospinal fluid cell slides, use the Cy-tosoin4 cell slide centrifuge method to prepare slides, centrifuge at 1000r / min for 5min, take out the cell slides, dry naturally, and use MGG routine staining , to make the cell structure and components colored and made into a stained sheet, which is the key and basis for observing the cell size, shape and structural characteristics and labeling work under the microscope image analyzer in the later stage; ...

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Abstract

The invention discloses an automatic cerebrospinal fluid cell analysis system based on artificial intelligence. The system comprises an establishment method of a cerebrospinal fluid cell image featurelibrary, a cerebrospinal fluid cell image feature acquisition method and device, and an automatic cerebrospinal fluid cell image identification and counting method. The invention overcomes the defects in the prior art, and provides a cerebrospinal fluid cell image library establishment method, a cerebrospinal fluid cell image acquisition method and device, and a cerebrospinal fluid cell image automatic identification and counting method. Feature extraction is automatically carried out on a cerebrospinal fluid cell image, pixel-level segmentation is carried out on cerebrospinal fluid cells, the segmented cerebrospinal fluid cells are classified, and cells of the whole cerebrospinal fluid cell image are counted. According to the invention, the working efficiency of brain cell detection is greatly improved, the labor intensity of workers is reduced, and an important cerebrospinal fluid cell detection means is provided for the diagnosis of diseases such as central nervous system infection, meningeal leukemia, lymphoma, cerebral parasitic diseases, cerebrovascular diseases, immune degeneration and the like.

Description

technical field [0001] The invention belongs to the technical field of cytological detection of cerebrospinal fluid, and in particular relates to an automatic analysis system of cerebrospinal fluid cells based on artificial intelligence. Background technique [0002] Cerebrospinal fluid is a colorless, transparent, viscous fluid located between the arachnoid and meninges of the meninges and in the spinal cord. It is produced by specialized ependymal cells in the choroidal plexus of the ventricle and is taken up by arachnoid granules. There is about 125mL of cerebrospinal fluid in each human body, and about 500mL is produced every day. It is a pure physiological saline containing microglial cells, mainly used as a mechanical buffer for the cerebral cortex, providing basic mechanical and immune protection for the brain inside the skull, and also plays a vital role in the automatic regulation of cerebral blood flow in the brain important role. Cerebrospinal fluid occupies th...

Claims

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Application Information

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IPC IPC(8): G01N15/10G01N1/28G01N1/30G06K9/32G06K9/62G06N3/04G06N3/08G06T7/00G06T7/11
CPCG01N15/10G01N1/2813G01N1/30G06T7/0012G06T7/11G06N3/08G01N2015/1006G01N2001/2846G06T2207/10056G06T2207/30016G06T2207/30242G06V10/25G06N3/045G06F18/2431G06F18/214G01N2015/1022
Inventor 王振海王士林马晓峰王国玮张群吴若芬侯玉婷王妍柏孔繁元
Owner GENERAL HOSPITAL OF NINGXIA MEDICAL UNIV
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