Traditional chinese medicine compound for relieving eczema, and slow-release agent as well as preparation method and application

Abstract

The invention relates to the technical field of traditional chinese medicines, in particular to a traditional chinese medicine compound for relieving eczema, and a slow-release agent as well as a preparation method and application. The traditional chinese medicine compound is prepared from the following raw materials of scutellaria baicalensis, coptis chinensis, divaricate saposhnikovia root and atractylodes lancea. According to the traditional chinese medicine compound for relieving eczema, and the slow-release agent as well as a preparation method and application, after a traditional chinesemedicine is nanocrystallized, the bioavailability of the medicine can be improved, the onset time of the medicine is advanced, and the medicine effect of the original medicine is enhanced; a nano-scale molecular material is used as a carrier material to carry the medicine, so that the medicine is adsorbed or coated in the nano-carrier, the release time of the medicine can be delayed, and the medicine can be automatically released at a preset speed within preset time; and by increasing the dissolution rate of active ingredients of the traditional chinese medicine, the variety of pharmaceuticaldosage forms can be increased, and the development of multiple products such as gel paste, mist and emulsion is facilitated; and by using a proper gel carrier, the traditional chinese medicine compound can be promoted to permeate into corresponding epidermal cells to enter targets, the medicine effect for relieving eczema is improved, and the unstable medicine effect, caused by uneven dissolution, for relieving eczema is reduced.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, more specifically, the invention relates to a traditional Chinese medicine compound for alleviating eczema, a slow-release agent, a preparation method and an application. Background technique [0002] In the era of drug delivery system (DDS), pharmaceutical preparations have entered the stage of intelligent drug delivery system after going through the stages of conventional preparations, long-acting and sustained-release preparations, controlled-release preparations and targeted preparations. A preparation is no longer just a drug "formulation" with a certain dosage form, but a "device" for delivering and delivering drugs. Nano-carrier technology is to use a nano-scale molecular material as a carrier material to carry drugs, so that drugs can be adsorbed or encapsulated in nano-carriers. The properties of the drug change significantly after nanonization, mainly because the a...

AI Technical Summary

Problems solved by technology

[0008] 4 Conducive to the standardization and internationalization of traditional Chinese medicine and its single dosage form, the processing technology is cumbersome and backward, the quality standard is poorly controllable, and the international market sales share is very small

However, in the current process of preparing nano-sized traditional Chinese medicine, there are cumbersome preparations, poor stability, and uneven sustained-release effects.

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