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Inula nervosa wall composite extract as well as preparation method and application thereof

A technology of showing pulse inula and compound extract, applied in the field of food or medicine, can solve the problem of stimulating the demand of ulcerative colitis, and achieve the effects of small side effects, safety guarantee and increased safety.

Inactive Publication Date: 2021-03-19
KUNMING UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have significant side effects, which has fueled the need for safe and effective drugs for the treatment of ulcerative colitis

Method used

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  • Inula nervosa wall composite extract as well as preparation method and application thereof
  • Inula nervosa wall composite extract as well as preparation method and application thereof
  • Inula nervosa wall composite extract as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0042] 1. The rhizomes and petals of Inula variegata collected from Kunming City, Yunnan Province were pulverized into 500nm particle diameters by a pulverizer respectively, and then subjected to 600Mpa ultra-high pressure treatment for 15 minutes to obtain samples of inula rhizomes and petals; Veining Inula rhizome and petal samples, according to the ratio of material to liquid 1kg: 15L, were extracted with aqueous solution at 60°C ultrasonic (20kHz) for 1h, centrifuged at 8000r / min for 10min to get the supernatant, concentrated by rotary evaporation at 55°C to obtain Veining Inula Water extract of flower rhizome and water extract of inula petals.

[0043] 2. Combine the water extract of Inula inula inulata rhizome and the petals in Inula inula inula inulata with tartary buckwheat, camellia japonica, Gastrodia elata, kudzu powder and ethanol solution that have been pulverized into 500nm particle size by a pulverizer according to 1L: Mix 2kg: 2kg: 5kg: 5kg: 20L, microwave extr...

Embodiment 2

[0045] 1. The rhizomes and petals of Inula inula variegata collected from Kunming City, Yunnan Province were pulverized to a particle size of 10nm by a pulverizer respectively, and then subjected to 200Mpa ultra-high pressure treatment for 30min to obtain samples of inula inula inula inflexa and inula rhizomes and petals; Veining Inula rhizome and petal samples, according to the ratio of material to liquid 1kg: 1L, were extracted with aqueous solution at 30°C ultrasonic (20kHz) for 5h, centrifuged at 8000r / min for 10min to get the supernatant, concentrated by rotary evaporation at 45°C to obtain Veining Inula Water extract of flower rhizome and water extract of inula petals.

[0046] 2. Combine the water extract of Inula inula inulae rhizome and water extract in Inula inula inula inulae with petal water extract, respectively, with tartary buckwheat, golden camellia, Gastrodia elata, kudzu powder and ethanol solution crushed to a particle size of 10nm by a pulverizer according to ...

Embodiment 3

[0048] 1. The rhizomes and petals of Inula variegata collected from Kunming City, Yunnan Province were crushed by a pulverizer until the particle size was 250nm, and then subjected to 450Mpa ultra-high pressure treatment for 10 minutes to obtain the rhizome and petal samples of Inula variegata; weigh 1kg respectively The rhizome and petals of Inula inula veinensis, according to the ratio of solid to liquid 1kg: 50L, were extracted with aqueous solution at 50°C ultrasonic (20kHz) for 3.5h, centrifuged at 8000r / min for 10min to take the supernatant, concentrated by rotary evaporation at 50°C to obtain the veins Inula Rhizome Water Extract and Inula Inula Petal Water Extract.

[0049] 2. Combine the water extract of Inula inula rhizome and the water extract of Inula inula inula and the water extract of Inula inula inula and the solution of tartary buckwheat, camellia japonica, Gastrodia elata, kudzu powder and ethanol, which are crushed to a particle size of 250nm, respectively, a...

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Abstract

The invention provides a preparation method and application of an inula nervosa wall composite extract. The preparation method of the inula nervosa wall composite extract comprises the following stepsof crushing inula nervosa wall, adding an aqueous solution for ultrasonic extraction, performing centrifugation to obtain a supernatant, and performing concentration to obtain an inula nervosa wall aqueous extract; and then, uniformly mixing the inula nervosa wall aqueous extract, tartary buckwheat, camellia nitidissima, rhizoma gastrodiae, pueraria lobata and an ethanol solution, performing microwave-assisted extraction, performing centrifugation to obtain a supernatant, performing concentration, and performing drying to obtain the inula nervosa wall composite extract. The inula nervosa wallextract prepared by the preparation method has an excellent effect of improving inflammatory bowel diseases, and has the advantages of safety, health and easily available raw materials; and in combination with the reasons, the inula nervosa wall extract has relatively good development and utilization prospects in the preparation of drugs or functional foods for prevention and adjuvant treatment of ulcerative colitis and Crohn's disease.

Description

technical field [0001] The invention relates to a compound extract of Inula inula venosa and its preparation method and application, which belong to the technical field of food or medicine. Background technique [0002] Inula inula, commonly known as Xiaoheiyao, also known as Yunweiling, Weilingcao, etc., is mainly distributed in northern Yunnan, southwestern Sichuan, northern Guizhou and western Guangxi. It is a commonly used ethnic medicine in Yunnan, Guizhou and other places. It is mainly used In the treatment of cough, bruises, rheumatic bone pain, indigestion, neurasthenia and other symptoms. In 2010, Inula inula was approved by the Ministry of Health as a new food raw material. Studies have shown that the extract of Inula japonicus has a good antioxidant effect. However, there is no report about the improvement of inflammatory bowel disease by the extract of Inula vegetalis. At present, there is no literature report on the related research on the prevention and trea...

Claims

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Application Information

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IPC IPC(8): A23L33/105A23L5/20A23L5/30A23L5/00A61K36/8988A61P1/00A61P1/04
CPCA23L33/105A23L5/20A23L5/32A23L5/34A23L5/00A61K36/28A61K36/70A61K36/82A61K36/8988A61K36/488A61P1/00A61P1/04A23V2002/00A61K2236/331A61K2236/33A61K2236/51A61K2236/53A23V2250/21A23V2250/214A23V2300/46A23V2300/48A23V2200/32A61K2300/00
Inventor 李莉蓉杨振光覃宇悦李凤洁
Owner KUNMING UNIV OF SCI & TECH
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