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Disinfection method and system for inactivating novel coronavirus in cold-chain food through ionizing radiation

A technology of ionizing radiation and coronavirus, applied in the fields of food preservation, food science, application, etc., can solve the problem of inability to sterilize food with ionizing radiation in cold chain, and achieve the effect of ensuring people's health and safety, no heat-producing effect, and strong penetrating power.

Active Publication Date: 2021-02-05
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above dose has far exceeded the tolerance dose of the food itself, and obviously cannot be used for ionizing radiation disinfection of cold chain food

Method used

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  • Disinfection method and system for inactivating novel coronavirus in cold-chain food through ionizing radiation
  • Disinfection method and system for inactivating novel coronavirus in cold-chain food through ionizing radiation
  • Disinfection method and system for inactivating novel coronavirus in cold-chain food through ionizing radiation

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach

[0046] High-energy electron beam inactivation test for novel coronavirus, the specific implementation method is as follows:

[0047] In a biosafety level-three laboratory authorized by the national disease control department, the samples of the new coronavirus strain were loaded into frozen Ecuadorian white shrimp samples, and packaged in multiple layers in a biosafety transfer bag. Before transfer, the outer surface of the transfer bag and the Biosafety transport boxes for chemical disinfection.

[0048] Sterilization by ionizing radiation using a 10 MeV electron beam. The process parameters are: power 15 kw, repetition frequency 335 Hz, beam energy 10 MeV, beam transmission rate 8 m / min, absorbed dose with 10 gradients, and the dose range is 1-10 kGy.

[0049] The virus pre-loaded in the frozen Ecuadorian white shrimp sample after irradiation was taken out to infect Vero cells, and the cytopathic effect was observed after 72 hours of culture, and the one-step novel coronavi...

Embodiment 2

[0053] The gamma ray device inactivates the new coronavirus test, the specific implementation method is as follows:

[0054] In a biosafety level-three laboratory authorized by the national disease control department, the samples of the new coronavirus strain were loaded into frozen Ecuadorian white shrimp samples, and packaged in multiple layers in a biosafety transfer bag. Before transfer, the outer surface of the transfer bag and the Biosafety transport boxes for chemical disinfection.

[0055] A 1.2 million curie cobalt-60 irradiation source was used for ionizing radiation disinfection. The process parameters are: the distance between the cargo carrier and the nearest end of the plate source is 200 mm, and the absorbed dose is set in 3 gradients, and the dose range is 2-7 kGy.

[0056] The virus pre-loaded in the frozen Ecuadorian white shrimp sample after irradiation was taken out to infect Vero cells, and the cytopathic effect was observed after 72 hours of culture, and...

Embodiment 3

[0060] The X-ray device inactivates the new coronavirus test, the specific implementation method is as follows:

[0061] In a biosafety level-three laboratory authorized by the national disease control department, the samples of the new coronavirus strain were loaded into frozen Ecuadorian white shrimp samples, and packaged in multiple layers in a biosafety transfer bag. Before transfer, the outer surface of the transfer bag and the Biosafety transport boxes for chemical disinfection.

[0062] Electron accelerators are installed with conversion targets to generate X-rays for ionizing radiation disinfection. The process parameters are: power 100kw, beam energy 5 MeV, conversion target material is high-purity tungsten target, conversion target cooling system is water cooling cycle, transmission rate under the beam is 2 m / min, absorbed dose is set to 3 gradients, and the dose range is 2- 7 kGy.

[0063] The virus pre-loaded in the frozen Ecuadorian white shrimp sample after irr...

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Abstract

The invention relates to a disinfection method and system for inactivating novel coronavirus in cold-chain food through ionizing radiation, and belongs to the technical field of disinfection and sterilization. Electron beams with the energy not higher than 10 MeV generated by an electron accelerator or gamma rays generated by cobalt-60 or cesium-137 radionuclide or X rays with the energy not higher than 5 MeV generated by an electron accelerator are adopted, on the premise of ionizing radiation disinfection whole-process biological safety guarantee, within determined effective dose range (2-7kGy), the cold-chain food which is possibly polluted by the novel coronavirus (2019-nCoV) is thoroughly inactivated on inner and outer surfaces of packages, food surfaces and food gaps of the cold-chain food in combination with a matched special disinfection system, the inactivation rate of the novel coronavirus is larger than 99.9%, and the novel coronavirus after irradiation does not have infection and pathogenicity any more.

Description

technical field [0001] The invention belongs to the technical field of disinfection and sterilization, and in particular relates to a disinfection method and system for ionizing radiation inactivation of novel coronavirus in cold chain food. Background technique [0002] Since the outbreak of the global new crown epidemic, as of December 21, 2020, according to the epidemic data released by Johns Hopkins University in the United States, the cumulative number of confirmed cases of new coronary pneumonia in the world has reached 76.82 million, and the cumulative number of deaths has exceeded 1.69 million. Following the domestic food contamination incident at Xinfadi in Beijing, on July 3, 2020, Dalian Customs detected positive nucleic acid for the novel coronavirus from one sample of the inner wall and three samples of the outer packaging of a container loaded with frozen vannamei shrimp produced in Ecuador. On October 17 of the same year, during the investigation of the origin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L3/32
CPCA23L3/26A23L3/263
Inventor 叶庆富姚航平张素芬余志扬王伟翁天豪
Owner ZHEJIANG UNIV
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