Traditional Chinese medicine for preventing and treating cerebral arterial thrombosis

An ischemic stroke, traditional Chinese medicine technology, applied in drug combinations, pharmaceutical formulations, cardiovascular system diseases, etc., can solve problems such as side effects, gastrointestinal and nervous system damage, hidden dangers, etc.

Inactive Publication Date: 2021-01-26
大连正源中医门诊部有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Naoxintong Capsules also have certain side effects. Long-term use can cause symptoms such as nausea, diarrhea, dizziness, headache, insomnia, fatigue, and fever. It has hidden dangers to the gastrointestinal tract and nervous system, and the adverse reactions may be Related to scorpion toxicity in medicine

Method used

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  • Traditional Chinese medicine for preventing and treating cerebral arterial thrombosis
  • Traditional Chinese medicine for preventing and treating cerebral arterial thrombosis

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0010] 1. Experimental animals

[0011] Sixty SPF-grade male KM mice, weighing 25±5g, were provided by the SPF Animal Experiment Center of Dalian Medical University [animal use license number: SYXK-(Liao) 2018-0007].

[0012] 2. Drugs and devices

[0013] Antithrombotic pills (honeyed pills made in the examples of the present invention); Xinnaokang Capsules (Jilin Mizhikang Pharmaceutical Co., Ltd., approval number: Z22025480); L-type carrageenan (Shanghai Jinsong Industrial Co., Ltd. Company); chloral hydrate (Shanghai Xinyu Biotechnology Co., Ltd.); normal saline (Jiangxi Keda Sanitary Products Company); disposable sterile syringe (Dalian JMS Medical Appliance Co., Ltd.); vernier caliper (Japan Mitutoyo Instruments); Stomach needle (Beijing Heli Science and Technology Development Co., Ltd.).

[0014] 3. Experimental method

[0015] 3.1 Grouping and administration

[0016] The male KM mice that were adaptively fed for one week were randomly divided into six groups, 10 in ...

experiment example 2

[0036] 1. Experimental animals SPF grade male SD rats (SPF Animal Experiment Center, Dalian Medical University, animal use license number: SYXK-(Liao) 2018-0007).

[0037] 2. Drugs and devices

[0038] Antithrombotic pills (honeyed pills made in the examples of the present invention); Naoxintong capsules (Shaanxi Buchang Pharmaceutical Co., Ltd., approval number: Z20025001, specifications: 0.4g·36 capsules / box); Danshen (purchased at Dalian Tongrentang Pharmacy, place of origin: Henan) Epinephrine Hydrochloride Injection ( Adrenaline Hydrochloride Injection, Adrenaline ) (Shanghai Hefeng Pharmaceutical Co., Ltd., approval number: Guoyao Zhunzi H31021062, specification: 1ml:1mg).

[0039] SA-9000 automatic hemorheology instrument (Beijing Seikexide Technology Co., Ltd.); RC-6plus ground into a high-speed refrigerated centrifuge (Thermo Fisher Scientific Co., Ltd., USA); disposable human vein collection container (Zhengzhou Shanshan Medical Supplies Co., Ltd.); BSA4202S Elect...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for preventing and treating cerebral arterial thrombosis. The traditional Chinese medicine comprises the following raw material components in mass ratio: 1000 of agkistrodon halys powder, 1000 of radix astragali powder, 500 of caulis spatholobi powder, 100 of hirudo powder, 100 of pheretima powder, 100 of rhizoma chuanxiong powder, 100 of radix salvia miltiorrhiza powder, 100 of rhizoma gastrodiae powder and 1 of moschus powder. Agkistrodon halys and radix astragali are monarch drugs and have the effects of tonifying qi and activating blood; rhizoma gastrodiae, hirudo and radix salviae miltiorrhizae are used as ministerial drugs for eliminating phlegm and removing blood stasis; rhizoma chuanxiong, caulis spatholobi, pheretima and moschus are assistant and guide each other to activate blood and promote blood circulation and enter brain orifices; and all the medicines are combined to achieve the effects of promoting blood circulation, removing blood stasis, tonifying deficiency and dredging collaterals, and the traditional Chinese medicine is safe to take and free of side effects, and can be used for preventing and treating cerebral arterial thrombosis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine which is safe to take and has good effect for preventing and treating ischemic stroke. Background technique [0002] Ischemic stroke, also known as cerebral infarction, is called stroke or apoplexy in traditional Chinese medicine. It is caused by a variety of reasons for localized brain tissue regional blood supply disorders, resulting in brain tissue ischemic and hypoxic lesions and necrosis, which in turn produces clinically corresponding symptoms. neurological deficits. According to different pathogenesis, it is divided into cerebral thrombosis, cerebral embolism and lacunar infarction, etc. It is a high-incidence and high-risk cerebrovascular disease. At present, Western medicine intravenous thrombolysis and endovascular treatment are mainly used clinically, generally within 4.5 hours and 6 hours of the onset of the disease, and the later perio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P9/10A61K35/55A61K35/583A61K35/62
CPCA61K35/55A61K35/583A61K35/62A61K36/236A61K36/481A61K36/486A61K36/537A61K36/8988A61P9/10A61K2300/00
Inventor 郁万刚田源郑洪新李敬林张琳李光星张柳丁凯悦王振林希钒
Owner 大连正源中医门诊部有限公司
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