Anti-pollution degerming nanofiber filter membrane and preparation method thereof

Abstract

The invention provides an anti-pollution degerming nanofiber filter membrane and a preparation method thereof. The preparation method comprises the following steps: preparing polyvinyl alcohol-ethylene copolymer nanofibers with a diameter of 50-300 nm by adopting a melt blending phase separation method; then preparing a suspension, and coating the surface of a non-woven fabric base material to obtain a nanofiber thin layer with a thickness of 2-10 [mu]m and a pore diameter of 90-130 nm; and after a grafted compound is adsorbed on the surface of the nanofiber thin layer, carrying out plasma treatment to form chemical bonding grafting so as to obtain the nanofiber filter membrane with anti-pollution and sterilization functions is obtained. According to the invention, an amphiphilic compoundand / or a compound containing olefin double bonds and at least one of carboxyl and sulfonic acid groups are grafted on the surface of a polyvinyl alcohol-ethylene copolymer nanofiber membrane, so thatbacteria can be efficiently intercepted, and the adsorption of BSA can be reduced so as to inhibit the adsorption growth of bacteria on the surface of the membrane and significantly improve the anti-pollution capability of the membrane.

Description

technical field [0001] The invention belongs to the technical field of filter membranes, in particular to an anti-fouling and bacteria-removing nanofiber filter membrane and a preparation method thereof. Background technique [0002] Filtration sterilization technology has broad and attractive application prospects in the fields of biopharmaceuticals, food and beverage, medical treatment, chemical electronics, air purification, water treatment, and environmental protection. As the core of filtration and sterilization technology, the sterilization membrane affects and restricts the development and application of filtration and sterilization technology. Filtration sterilization is to pass the solution, gas, etc. that need to be sterilized, such as some pharmaceutical solutions, through a sterile specific filter membrane to remove live or dead microorganisms to obtain a microorganism-free filtrate or gas. For example: the use of filter membranes to remove microorganisms in sol...

AI Technical Summary

Problems solved by technology

At the same time, under the pressure of 0.1MPa, the serum protein was passed through a polyethersulfone microporous filter with a pore size of 1.2 μm, and it was found that the volume of serum protein passing through in 10 minutes was 85L, and the filtration rate was 510L / h; it was measured by the Chinese Pharmacopoeia sterility test method The sterilization rate is 96.875%, which cannot meet the sterilization requirements of the high-end field

[0004] In addition, the commonly used raw materials for membrane production such as PVDF (polyvinylidene fluoride), PSF (polysulfone) or polyethersulfone (PES) are linear polymers, and the distance between molecular chains is large, which makes the desalination effect poor.

Although the body structure can be formed by cross-linking, the functional groups of the hydrophilic cross-linking monomers are cross-linked and the functional groups are consumed, thereby reducing the hydrophilicity of the membrane.

Since the hydrophilicity of the material has a great influence on the flux and antifouling performance of the membrane, the flux and antifouling performance are also reduced

At the same time, microorganisms and bacteria in the water will deposit and multiply on the surface of the sterilizing filter membrane during use, forming a biofilm and polluting the sterilizing filter membrane, resulting in a sharp decrease in the membrane flux.

Images