High-field asymmetric waveform ion mobility spectrometer

Abstract

The invention discloses a plate type high-field asymmetric waveform ion mobility spectrometer. The ion mobility spectrometer comprises an ion source, a migration region and a detection region, whereinthe migration region comprises an electrode pair composed of an upper electrode and a lower electrode, one electrode is a grid-type plate electrode, and the other electrode is a metal plate electrode. Asymmetric waveform voltage is applied to the electrode pair, and an asymmetric waveform electric field which is non-uniformly distributed in space can be generated in the migration region. Under the electric field, specific ions generate a movement trend towards the central plane of the migration region in the migration region, i.e., ion focusing in the migration region is generated. The diffusion loss of the ions in the migration region is reduced due to ion focusing in the migration region, so that the passing efficiency of the ions in the migration region is improved. According to the ion mobility spectrometer, the sensitivity of the instrument can be improved, and under the same condition, the signal intensity measured by the ion mobility spectrometer is remarkably improved comparedwith the signal intensity of an existing plate type asymmetric waveform ion mobility spectrometer.

Description

technical field [0001] The invention relates to a high-field asymmetric waveform ion mobility spectrometer, in particular to a flat-plate high-field asymmetric waveform ion mobility spectrometer, and belongs to the field of biochemical substance on-line detection technology and equipment technology. Background technique [0002] High-field asymmetric waveform ion mobility spectrometer is an on-line detection technology for biochemical substances gradually developed in the 1990s. Its basic principle is that ion mobility has nothing to do with electric field strength under low electric field conditions. / cm, the mobility of ions will change nonlinearly with the electric field strength. The relationship between ion mobility and electric field strength under high field can be expressed by the following formula: [0003] K=K 0 [1+α 1 (E / N) 2 +α 2 (E / N) 4 +···], [0004] In the formula, K is the mobility of ions under high electric field, K 0 is the mobility of ions under ...

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Problems solved by technology

[0007] The purpose of the present invention is to provide a flat-plate high-field asymmetric waveform ion mobility spectrometer for the deficiencies and defects of the prior art, so as to solve the problem that the flat-plate high-field asymmetric waveform ion mobility spectrometer cannot achieve ion mobility within the migration region. focused question

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