Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Mercury-responsive fluorescent probe and preparation method thereof

A technology of fluorescent probes and synthesis methods, applied in fluorescence/phosphorescence, chemical instruments and methods, luminescent materials, etc., can solve the problems of complicated operation, complicated instruments, time-consuming, etc., and achieve good selectivity, high sensitivity, and post-processing. Simple process effect

Pending Publication Date: 2020-10-16
CHINA THREE GORGES UNIV
View PDF0 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the disadvantages of these methods are complex instruments, complex operations, difficult and time-consuming pretreatment, and are difficult to be popularized.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Mercury-responsive fluorescent probe and preparation method thereof
  • Mercury-responsive fluorescent probe and preparation method thereof
  • Mercury-responsive fluorescent probe and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Add 50 mg (0.14 mmol) of 2,5-bis(benzo[d]thiazol-2-yl)phenol and 28.3 mg (0.28 mmol) of triethylamine into the reaction flask, while adding 3 ml of dry redistilled dichloromethane as Solvent, then add 35.9 mg (0.21 mmol) of phenyl thiochloroformate under ice bath conditions and react for 0.5 h, then monitor the reaction by TLC spot plate until the reaction of the raw materials is complete, and pass the eluent according to the ratio of PE:DC=2:3 The column obtains the target product, and the productive rate is 38%, and the reaction formula is as follows:

[0020]

Embodiment 2

[0022] Add 50 mg (0.14 mmol) of 2,5-bis(benzo[d]thiazol-2-yl)phenol and 21.2 mg (0.21 mmol) of triethylamine into the reaction flask, while adding 3 ml of dry redistilled dichloromethane as Solvent, then add 35.9 mg (0.21 mmol) of phenyl thiochloroformate under ice bath conditions and react for 0.5 h, then monitor the reaction by TLC spot plate until the reaction of the raw materials is complete, and pass the eluent according to the ratio of PE:DC=2:3 Column obtains target product, and yield rate is 49%, and reaction formula is as follows:

[0023]

Embodiment 3

[0025] Add 50 mg (0.14 mmol) of 2,5-bis(benzo[d]thiazol-2-yl)phenol and 21.2 mg (0.21 mmol) of triethylamine into the reaction flask, while adding 5 ml of dry redistilled dichloromethane as Solvent, then add 35.9 mg (0.21 mmol) of phenyl thiochloroformate under ice bath conditions and react for 0.5 h, then monitor the reaction by TLC spot plate until the reaction of the raw materials is complete, and pass the eluent according to the ratio of PE:DC=2:3 Column obtains target product, and yield rate is 42%, and reaction formula is as follows:

[0026]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method and application of a ratio type divalent mercury fluorescent probe. The structural formula of the divalent mercury fluorescent probe is shown in the specification. The invention also provides a preparation method of the probe. The fluorescent probe shows blue fluorescence in a buffer solution and can carry out a specific reaction with mercuric chlorideto generate a product emitting yellow fluorescence, so that specific response to mercury is realized, and the probe also has good selectivity on divalent mercury.

Description

technical field [0001] The invention discloses a fluorescent probe capable of detecting heavy metal divalent mercury ions and its synthesis method and application, specifically relates to a fluorescent probe capable of detecting heavy metal divalent mercury ions through different emission wavelengths, belonging to chemical analysis and detection technology field. Background technique [0002] Heavy metal ions play an extremely important role in the fields of natural environment, physics and chemistry, among which mercury ion is a chemical substance with strong toxicity, which has the characteristics of persistence, easy migration and high bioaccumulation. This makes it one of the most attention-grabbing environmental pollutants in the world. It can weaken the central nervous system, cause nervous disorders, and pose certain threats to the kidneys, liver, digestive system, and hematopoietic system. Because after mercury enters the human body, it is quickly oxidized into merc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07D277/66C09K11/06G01N21/64
CPCC07D277/66C09K11/06C09K2211/1014C09K2211/1037G01N21/643
Inventor 郑开波王丽红
Owner CHINA THREE GORGES UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com