A kind of traditional Chinese medicine composition for treating ischemic stroke and its application

Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating ischemic stroke and application thereof. This recipe is composed of six herbs such as raw astragalus, raw rehmannia, raw scutellaria, Jiu Dilong, raw pueraria, and raw safflower. The invention can reduce the volume of cerebral infarction, reduce nerve function damage, reduce MDA content in brain tissue, and increase SOD activity; increase 6-keto-PGF 1α content, reducing TXB 2 content. It is suggested that the invention has the functions of resisting free radical damage, antithrombotic, improving fibrinolytic activity, and dissolving thrombosis and eliminating thrombosis. Compared with Naoxintong and other comparative inventions, the present invention has a significant protective effect on cerebral ischemia-reperfusion injury; at the same time, compared with the different dosage ratios of the present invention, the formulation of the present invention is more scientific. This experiment provides a reference for studying the mechanism of the present invention to protect cerebral ischemia-reperfusion injury, and provides an experimental basis for its clinical application in cerebral blood vessels.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating ischemic stroke and its application. Background technique [0002] Ischemic stroke (called ischemic stroke in traditional Chinese medicine) seriously endangers human life and quality of life, and has the characteristics of high mortality, morbidity, disability and recurrence. For the top three, the high disability rate and recurrence rate have brought a heavy burden to the society. Ischemic stroke accounts for about 50% to 65% of cerebrovascular diseases, and the disease has become an important topic of concern in the medical community at home and abroad. [0003] At present, traditional Chinese medicines for the treatment of ischemic stroke are mostly based on Qi deficiency and blood stasis. They are treated with nourishing qi and activating blood or blood activating drugs, and using Buyang Huanwu Decoction (suc...

AI Technical Summary

Problems solved by technology

[0003] At present, Chinese patent medicines for the treatment of ischemic stroke are mostly based on qi deficiency and blood stasis, and are treated with nourishing qi and activating blood or blood activating medicines, such as Buyang Huanwu Decoction (such as Naoxintong Capsules, Naofukang, Tongxinluo Capsules, Naoluo An et al.), although there are curative effects, but most of them are "replenishing qi and activating blood", which can easily cause injury to yin and reduce dryness, aggravate heat stasis, cerebral hemorrhage, cerebral ischemia-reperfusion injury and other disadvantages, and the curative effect needs to be improved.

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